Botulinum toxin type A in children and adolescents with severe cerebral palsy: a retrospective chart review.
J Child Neurol
; 29(2): 210-3, 2014 Feb.
Article
em En
| MEDLINE
| ID: mdl-23965398
ABSTRACT
This retrospective cohort study reviewed set goals and their outcomes of children and adolescents with severe cerebral palsy who received botulinum toxin A in 2008 and 2009. Sixty children (36 male, mean age 9 years) were included. They received on average 4 (range 1-7) treatments, with the dosage varying between 20 and 400 units per treatment (3-21 U/kg/body weight). Mild transient side effects were reported in 12 of 242 treatments with botulinum toxin A. Treatment goals were related to lower limb function (82%), range of motion (68%), positioning (33%), upper limb function (33%), and facilitating ease of care in dressing (30%), toileting, and diapering (22%). The treatment goals were reached in 60% to 85% by report of the parent and child dyad. Our findings suggest that botulinum toxin A should be considered as a treatment option in patients with cerebral palsy within Gross Motor Function Classification System levels IV and V.
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Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Paralisia Cerebral
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Toxinas Botulínicas Tipo A
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Fármacos Neuromusculares
Idioma:
En
Ano de publicação:
2014
Tipo de documento:
Article