Acute pain relief after Mantram meditation in children with neuroblastoma undergoing anti-GD2 monoclonal antibody therapy.
J Pediatr Hematol Oncol
; 36(2): 152-5, 2014 Mar.
Article
em En
| MEDLINE
| ID: mdl-24065045
ABSTRACT
Nonpharmacologic, mind-body interventions are used to reduce anxiety in pediatric patients. Anti-ganglioside GD2 monoclonal antibody (anti-GD2 MoAb 3F8) therapy is the standard of care for high-risk neuroblastoma and pain is its major side effect. We performed a retrospective analysis of children undergoing anti-GD2 MoAb 3F8 treatment who received guided meditation. Meditation involved concentrating on the repetition of rhythmic, melodic sounds purported to slow breathing and induce a relaxation response. A total of 71% patients completed a session at first (n=19) or second attempt (n=5). Patients received fewer analgesic doses to manage anti-GD2 MoAb 3F8-induced pain when participating in meditation (n=17, mean=-0.4 dose, P<0.01). Mantram meditation is a feasible outpatient intervention associated with reduced analgesic requirements.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Dor
/
Meditação
/
Neuroblastoma
/
Antineoplásicos
Idioma:
En
Ano de publicação:
2014
Tipo de documento:
Article