Hyperglycemia following recovery from hypoglycemia worsens endothelial damage and thrombosis activation in type 1 diabetes and in healthy controls.

Ceriello, A; Novials, A; Ortega, E; Pujadas, G; La Sala, L; Testa, R; Bonfigli, A R; Genovese, S

Ceriello, A; Novials, A; Ortega, E; Pujadas, G; La Sala, L; Testa, R; Bonfigli, A R; Genovese, S.

Afiliação

Ceriello A; Department of Endocrinology, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain; Spanish Biomedical Research Centre in Diabetes and Associated Metabolic Disorders (CIBERDEM), Spain. Electronic address: aceriell@clinic.ub.es.
Novials A; Department of Endocrinology, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain; Spanish Biomedical Research Centre in Diabetes and Associated Metabolic Disorders (CIBERDEM), Spain.
Ortega E; Department of Endocrinology, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain; Spanish Biomedical Research Centre in Diabetes and Associated Metabolic Disorders (CIBERDEM), Spain.
Pujadas G; Department of Endocrinology, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain; Spanish Biomedical Research Centre in Diabetes and Associated Metabolic Disorders (CIBERDEM), Spain; Metabolic and Nutrition Research Center on Diabetes, I
La Sala L; Department of Endocrinology, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain.
Testa R; Department of Endocrinology, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain; Spanish Biomedical Research Centre in Diabetes and Associated Metabolic Disorders (CIBERDEM), Spain; Metabolic and Nutrition Research Center on Diabetes, I
Bonfigli AR; Metabolic and Nutrition Research Center on Diabetes, Italian National Research Center on Aging, INRCA-IRCCS, Ancona, Italy.
Genovese S; Department of Cardiovascular and Metabolic Diseases, IRCCS Gruppo Multimedica, Sesto San Giovanni (MI), Italy.

Nutr Metab Cardiovasc Dis ; 24(2): 116-23, 2014 Feb.

Article em En | MEDLINE | ID: mdl-24094827

Assuntos

Diabetes Mellitus Tipo 1/terapia; Endotélio Vascular/patologia; Hiperglicemia/tratamento farmacológico; Hipoglicemia/terapia; Trombose/patologia; Adulto; Antitrombina III/metabolismo; Ácido Ascórbico/administração & dosagem; Glicemia/metabolismo; Dinoprosta/análogos & derivados; Dinoprosta/metabolismo; Feminino; Voluntários Saudáveis; Humanos; Hiperglicemia/etiologia; Hipoglicemia/complicações; Masculino; Estresse Oxidativo/fisiologia; Selectina-P/metabolismo; Fragmentos de Peptídeos/metabolismo; Peptídeo Hidrolases/metabolismo; Inibidor 1 de Ativador de Plasminogênio/metabolismo; Precursores de Proteínas/metabolismo; Protrombina/metabolismo; Trombose/etiologia; Adulto Jovem; Fator de von Willebrand/metabolismo

Palavras-chave

Hyperglycemia; Hypoglycemia; Oxidative stress; Thrombosis

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Trombose / Endotélio Vascular / Diabetes Mellitus Tipo 1 / Hiperglicemia / Hipoglicemia Idioma: En Ano de publicação: 2014 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google