Liver metastases in close contact to hepatic veins ablated under vascular exclusion.
Eur J Surg Oncol
; 39(12): 1400-6, 2013 Dec.
Article
em En
| MEDLINE
| ID: mdl-24095104
ABSTRACT
BACKGROUND:
Liver metastases (LM) in close contact to hepatic veins (HV) are a frequent cause of unresectability. Reconstruction of hepatic veins is technically difficult and outcomes are poor. Intra-operative radiofrequency ablation (IRFA) with vascular exclusion (VE) may be a useful approach.METHODS:
Out of 358 patients operated for LM, 22 with LM close to a HV treated by IRFA under VE with at least one year of follow-up were included in this retrospective study. Technical success was evaluated at four months by CT scan of the ablated lesion. Complications; local, hepatic and extra-hepatic recurrence rates, and overall survival are reported.RESULTS:
The median number of metastases was 4.5 [range 1-12]. Seventeen patients had bilateral metastases. The median size of ablated lesions was 2 cm [range 1-5.5]. Seven complications occurred (1 Grade 1, 2 Grade 3b and 4 Grade IVa), with no mortality. No recurrence of ablated lesions was detected at four months or during follow-up. Seventeen patients had new or extra-hepatic lesions. Median overall survival for colorectal patients was 40 months 95%CI[17.5-not reached].CONCLUSIONS:
IRFA plus VE for LM in close contact to a HV is a novel approach, appearing to be a safe and effective technique which can extend the applications of liver metastases surgery.Palavras-chave
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Base de dados:
MEDLINE
Assunto principal:
Neoplasias Colorretais
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Ablação por Cateter
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Veias Hepáticas
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Neoplasias Hepáticas
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Recidiva Local de Neoplasia
Idioma:
En
Ano de publicação:
2013
Tipo de documento:
Article