Probing the amino acids critical for protein oligomerisation and protein-nucleotide interaction in Mycobacterium tuberculosis PII protein through integration of computational and experimental approaches.
Biochim Biophys Acta
; 1834(12): 2736-49, 2013 Dec.
Article
em En
| MEDLINE
| ID: mdl-24129075
Palavras-chave
2-OG; 2-oxoglutarate; AMPPNP; ATP-γS; Adenosine 5'-(ß,γ-imido) triphosphate; Adenosine 5'-[γ-thio]-triphosphate; Electrostatic interactions; ITC; Isothermal Titration Calorimetry; Isothermal titration calorimetry; Molecular docking; MtbPII; Mutagenesis; Mycobacterium tuberculosis PII protein; PIC; PISA; Protein Interaction Calculator server; Protein Interfaces, Surfaces and Assemblies server; Protein stability
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Proteínas de Bactérias
/
Modelos Moleculares
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Trifosfato de Adenosina
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Proteínas PII Reguladoras de Nitrogênio
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Multimerização Proteica
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Mycobacterium tuberculosis
Idioma:
En
Ano de publicação:
2013
Tipo de documento:
Article