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The effect of preoperative ß-blocker use and race on long-term survival after coronary artery bypass grafting.
O'Neal, Wesley T; Efird, Jimmy T; Landrine, Hope; Anderson, Curtis A; Davies, Stephen W; O'Neal, Jason B; Ferguson, T Bruce; Chitwood, W Randolph; Kypson, Alan P.
Afiliação
  • O'Neal WT; Department of Internal Medicine, Wake Forest University School of Medicine, Winston-Salem, North Carolina. Electronic address: woneal@wakehealth.edu.
  • Efird JT; East Carolina Heart Institute, Department of Cardiovascular Sciences, Brody School of Medicine, East Carolina University, Greenville, North Carolina; Center for Health Disparities, Brody School of Medicine, East Carolina University, Greenville, North Carolina.
  • Landrine H; Center for Health Disparities, Brody School of Medicine, East Carolina University, Greenville, North Carolina.
  • Anderson CA; East Carolina Heart Institute, Department of Cardiovascular Sciences, Brody School of Medicine, East Carolina University, Greenville, North Carolina.
  • Davies SW; Department of General Surgery, University of Virginia School of Medicine, Charlottesville, Virginia.
  • O'Neal JB; Department of Anesthesia, Critical Care, and Pain Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts.
  • Ferguson TB; East Carolina Heart Institute, Department of Cardiovascular Sciences, Brody School of Medicine, East Carolina University, Greenville, North Carolina.
  • Chitwood WR; East Carolina Heart Institute, Department of Cardiovascular Sciences, Brody School of Medicine, East Carolina University, Greenville, North Carolina.
  • Kypson AP; East Carolina Heart Institute, Department of Cardiovascular Sciences, Brody School of Medicine, East Carolina University, Greenville, North Carolina.
J Cardiothorac Vasc Anesth ; 28(3): 595-600, 2014 Jun.
Article em En | MEDLINE | ID: mdl-24139457
OBJECTIVE: To date, racial differences in the long-term survival of coronary artery bypass grafting (CABG) patients who receive preoperative ß-blockers have not been specifically examined. The purpose of this study was to examine the effect of preoperative ß-blockers on long-term survival among black CABG patients and to compare the magnitude of this effect with white patients. DESIGN: A retrospective cohort study. SETTING: A tertiary referral heart hospital. PARTICIPANTS: 13,354 patients undergoing CABG between 1992 and 2011. MEASUREMENTS AND MAIN RESULTS: Hazard ratios (HR) and 95% confidence intervals (CI) were computed using a Cox regression model. A total of 1,448 (62%) black and 6,094 (55%) white patients had a history of preoperative ß-blocker use. Among black patients, those receiving ß-blockers survived longer than those not receiving ß-blockers (adjusted HR = 0.77, 95% CI = 0.67-0.88). The survival advantage was comparable to that observed among white patients (adjusted HR = 0.88, 95% CI = 0.82-0.93). CONCLUSION: Black CABG patients benefited from preoperative ß-blockers and the magnitude of the effect was comparable to that among white patients.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ponte de Artéria Coronária / Antagonistas Adrenérgicos beta Idioma: En Ano de publicação: 2014 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ponte de Artéria Coronária / Antagonistas Adrenérgicos beta Idioma: En Ano de publicação: 2014 Tipo de documento: Article