Myeloid growth factors.
J Natl Compr Canc Netw
; 11(10): 1266-90, 2013 Oct 01.
Article
em En
| MEDLINE
| ID: mdl-24142827
ABSTRACT
Febrile neutropenia, a common side effect of myelosuppressive chemotherapy in patients with cancer, can result in prolonged hospitalization and broad-spectrum antibiotic use, often prompting treatment delays or dose reductions of drug regimens. Prophylactic use of myeloid growth factors (mainly the colony-stimulating factors filgrastim and pegfilgrastim) in patients of heightened risk can reduce the severity and duration of febrile neutropenia. The NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Myeloid Growth Factors provide recommendations on the use of these agents mainly in the oncology setting based on clinical evidence and expert consensus. This version includes revisions surrounding the issue of timing of pegfilgrastim administration. It also includes new sections on tbo-filgrastim, a recently approved agent that is biologically similar to filgrastim, and the role of myeloid growth factors in the hematopoietic cell transplant setting.
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Base de dados:
MEDLINE
Assunto principal:
Fatores Estimuladores de Colônias
/
Neutropenia Febril Induzida por Quimioterapia
Idioma:
En
Ano de publicação:
2013
Tipo de documento:
Article