Metastasectomy for gastrointestinal stromal tumors.
J Surg Oncol
; 109(1): 23-7, 2014 Jan.
Article
em En
| MEDLINE
| ID: mdl-24155153
ABSTRACT
Gastrointestinal stromal tumor (GIST) is the most common sarcoma of the intestinal tract. Improvements in understanding the molecular pathogenesis of GIST have resulted in novel treatment strategies combining surgery with tyrosine kinase inhibitors (TKIs). Metastasectomy in carefully selected patients who have stable or responsive disease on imatinib should be considered in the multidisciplinary setting. We review existing data on surgical cytoreduction in metastatic GIST while on targeted therapy and compare outcomes with either treatment alone.
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Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Tumores do Estroma Gastrointestinal
/
Metastasectomia
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Neoplasias Gastrointestinais
Idioma:
En
Ano de publicação:
2014
Tipo de documento:
Article