[Home-based infusion therapy--a feasible approach for chronically ill patients? A new path to provide superior patient care exemplified for Fabry's disease]. / Infusionsbehandlung in häuslicher Umgebung--ein praktikabler Ansatz für chronisch Kranke? Neue Wege der Versorgung am Beispiel des Morbus Fabry.
Dtsch Med Wochenschr
; 138(46): 2345-50, 2013 Nov.
Article
em De
| MEDLINE
| ID: mdl-24193859
ABSTRACT
BACKGROUND:
As there are scarce data from Germany addressing home-based infusion therapy in chronically ill patients, a study on transferring infusion therapy from in-patient-treatment to home care, exemplified for Fabry's disease, was conducted.METHODS:
A total of 69 patients on enzyme replacement infusion therapy (ERT with agalsidase alfa every two weeks) were enrolled in the open, non-controlled, multicentre, non-interventional observational study. After uneventful ERT in a hospital setting, intravenous treatment was administered at home by a specially-trained nurse. Primary outcome measure was change in patient satisfaction measured by an eleven-item Likert scale.RESULTS:
The in-home observation period lasted between 96 und 401 days (median 180; IQR 166-184). Patient satisfaction increased significantly with home-based therapy (pâ =â 0.001). A quality of life analysis (SF-36) demonstrated significant improvements in role-physical (pâ =â 0.003), bodily pain (pâ =â 0.032), vitality (pâ <â 0.001), social functioning (pâ =â 0.020), role-emotional (pâ =â 0.007), mental well-being (pâ =â 0.007) and mental sum score (pâ =â 0.002). Home infusions turned out to be safe and were well tolerated.CONCLUSION:
Chronically ill patients with need for regular infusion therapy may benefit from a home care setting. Home-based infusion therapy as exemplified by agalsidase alfa ERT in Fabry's disease is a viable option for patients who received uneventful infusions within the hospital.
Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Qualidade de Vida
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Doença Crônica
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Satisfação do Paciente
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Doença de Fabry
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Alfa-Galactosidase
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Terapia por Infusões no Domicílio
Idioma:
De
Ano de publicação:
2013
Tipo de documento:
Article