Sonication: a valuable technique for diagnosis and treatment of periprosthetic joint infections.
ScientificWorldJournal
; 2013: 375140, 2013.
Article
em En
| MEDLINE
| ID: mdl-24222731
ABSTRACT
BACKGROUND:
Periprosthetic joint infection (PJI) is the most severe complication, following joint arthroplasty. Identification of the causal microbial factor is of paramount importance for the successful treatment.PURPOSE:
The aim of this study is to compare the sonication fluid cultures derived from joint prosthetic components with the respective periprosthetic tissue cultures.METHODS:
Explanted prosthesis components for suspected infection were placed into a tank containing sterile Ringer's solution and sonicated for 1 minute at 40 kHz. Sonication fluid cultures were examined for 10 days, and the number and identity of any colony morphology was recorded. In addition, periprosthetic tissue specimens (>5) were collected and cultured according to standard practice. The duration of antimicrobial interruption interval before culture sampling was recorded.RESULTS:
Thirty-four patients composed the study group. Sonication fluid cultures were positive in 24 patients (70.5%). Sixteen of thirty four periprosthetic tissue cultures (47.1%) were considered positive, all revealing the same microbial species with the respective sonication fluid cultures 3 tissue samples showed polymicrobial infection. All tissue cultures were also found positive by the sonication fluid culture.CONCLUSIONS:
Sonication fluid cultures represent a cheap, easy, accurate, and sensitive diagnostic modality demonstrating increased sensitivity compared to periprosthetic tissue cultures (70.5 versus 47.1%).
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Sonicação
/
Infecções Relacionadas à Prótese
/
Biofilmes
/
Prótese Articular
Idioma:
En
Ano de publicação:
2013
Tipo de documento:
Article