Endobronchial avium mycobacteria infection in an immunocompetent child.
BMJ Case Rep
; 20132013 Nov 19.
Article
em En
| MEDLINE
| ID: mdl-24252838
ABSTRACT
A 12-month-old boy, with no medical history, was admitted for dyspnoea with no cough or fever. Chest auscultation revealed an expiratory wheezing with decreased right-sided breath sounds. Chest imaging revealed subcarinal adenopathy and a nodule in the right principal bronchus (RB). Bronchoscopy showed a major obstruction of the RB by a granuloma, and a smaller granuloma in the left principal bronchus. The granulation tissue was removed by laser section. Histological examination revealed a necrotising granulomatous inflammation, culture showed a Mycobacterium avium complex (MAC). Tests to rule out tuberculosis and immunodeficiency were negative. The diagnosis of an MAC endobronchial granuloma was ascertained and a multidrug therapy associating clarithromycin, rifampin and ethambutol was started. The clinical outcome was good after 3 months of treatment and the bronchoscopy normalised after 1 year. Although rare, the frequency of MAC respiratory infections in immunocompetent children can increase. Reporting these cases should help to optimise diagnosis and treatment.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Broncopneumonia
/
Complexo Mycobacterium avium
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Infecção por Mycobacterium avium-intracellulare
Idioma:
En
Ano de publicação:
2013
Tipo de documento:
Article