Hollow-fiber liquid-phase microextraction combined with capillary electrophoresis for trace analysis of sulfonamide compounds.
J Chromatogr B Analyt Technol Biomed Life Sci
; 942-943: 134-40, 2013 Dec 30.
Article
em En
| MEDLINE
| ID: mdl-24269907
ABSTRACT
A hollow-fiber liquid-phase microextraction (HF-LPME) method has been developed for the preconcentration of trace sulfonamides in water samples. Six commonly used sulfonamides including sulfamethazine (SMZ), sulfamerazine (SMR), sulfadiazine (SDZ), sulfadimethoxine (SDM), sulfamethoxazole (SMX), and sulfathiazole (STZ) were determined by CE with electrochemical detection (CE-ED) after microextraction. Several factors that affect extraction efficiency, separation, and detection were investigated. Under the optimum conditions, above sulfonamide compounds could achieve baseline separation within 35min, exhibiting a linear calibration over three orders of magnitude (r(2)≥0.998); the obtained enrichment factors were between 121 (for SDZ) and 996 (for SDM), and the LODs were in the range of 0.033-0.44ng/mL. The proposed HF-LPME/CE-ED method has been applied for the sensitive analyses of the real-world water samples with recoveries in the range of 75.1-109%.
Palavras-chave
Capillary electrophoresis; DLLME; ED; EFs; Electrochemical detection; HF-LPME; Hollow-fiber liquid-phase microextraction; LLE; PSS; SCE; SDM; SDME; SDZ; SLM; SMR; SMX; SMZ; STZ; Sulfonamides; Water analysis; dispersive liquidliquid microextraction; electrochemical detection; enrichment factors; hollow-fiber liquid-phase microextraction; liquidliquid extraction; saturated calomel electrode; single-drop liquid-phase microextraction; sodium polystyrene sulfonate; sulfadiazine; sulfadimethoxine; sulfamerazine; sulfamethazine; sulfamethoxazole; sulfathiazole; supported liquid membrane
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Sulfonamidas
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Poluentes Químicos da Água
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Eletroforese Capilar
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Microextração em Fase Líquida
Idioma:
En
Ano de publicação:
2013
Tipo de documento:
Article