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BCR-ABL disrupts PTEN nuclear-cytoplasmic shuttling through phosphorylation-dependent activation of HAUSP.
Morotti, A; Panuzzo, C; Crivellaro, S; Pergolizzi, B; Familiari, U; Berger, A H; Saglio, G; Pandolfi, P P.
Afiliação
  • Morotti A; 1] Cancer Research Institute, Beth Israel Deaconess Cancer Center, Department of Medicine and Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA [2] Division of Hematology and Internal Medicine, Department of Oncology, San Luigi Hospital, University of Turin, Tu
  • Panuzzo C; Division of Hematology and Internal Medicine, Department of Oncology, San Luigi Hospital, University of Turin, Turin, Italy.
  • Crivellaro S; Division of Hematology and Internal Medicine, Department of Oncology, San Luigi Hospital, University of Turin, Turin, Italy.
  • Pergolizzi B; Department of Clinical and Biological Sciences, University of Turin, Turin, Italy.
  • Familiari U; Division of Pathology, Department of Oncology, St Luigi Hospital, Torino, Italy.
  • Berger AH; Cancer Research Institute, Beth Israel Deaconess Cancer Center, Department of Medicine and Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
  • Saglio G; Division of Hematology and Internal Medicine, Department of Oncology, San Luigi Hospital, University of Turin, Turin, Italy.
  • Pandolfi PP; Cancer Research Institute, Beth Israel Deaconess Cancer Center, Department of Medicine and Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
Leukemia ; 28(6): 1326-33, 2014 Jun.
Article em En | MEDLINE | ID: mdl-24317448
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fatores de Transcrição / Proteínas Nucleares / Leucemia Mielogênica Crônica BCR-ABL Positiva / Núcleo Celular / Proteínas de Fusão bcr-abl / Citoplasma / Proteínas Supressoras de Tumor / Ubiquitina Tiolesterase / PTEN Fosfo-Hidrolase Idioma: En Ano de publicação: 2014 Tipo de documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fatores de Transcrição / Proteínas Nucleares / Leucemia Mielogênica Crônica BCR-ABL Positiva / Núcleo Celular / Proteínas de Fusão bcr-abl / Citoplasma / Proteínas Supressoras de Tumor / Ubiquitina Tiolesterase / PTEN Fosfo-Hidrolase Idioma: En Ano de publicação: 2014 Tipo de documento: Article