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Rational design and synthesis of topoisomerase I and II inhibitors based on oleanolic acid moiety for new anti-cancer drugs.
Ashour, Ahmed; El-Sharkawy, Saleh; Amer, Mohamed; Abdel Bar, Fatma; Katakura, Yoshinori; Miyamoto, Tomofumi; Toyota, Nozomi; Bang, Tran Hai; Kondo, Ryuichiro; Shimizu, Kuniyoshi.
Afiliação
  • Ashour A; Department of Agro-Environmental Sciences, Faculty of Agriculture, Kyushu University, Fukuoka, Japan; Department of Pharmacognosy, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt.
  • El-Sharkawy S; Department of Pharmacognosy, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt; Department of Pharmacognosy, Faculty of Pharmacy, Delta University for Science and Technology, Egypt.
  • Amer M; Department of Pharmacognosy, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt.
  • Abdel Bar F; Department of Pharmacognosy, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt.
  • Katakura Y; Department of Genetic Resources Technology, Faculty of Agriculture, Kyushu University, Fukuoka, Japan.
  • Miyamoto T; Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan.
  • Toyota N; Department of Agro-Environmental Sciences, Faculty of Agriculture, Kyushu University, Fukuoka, Japan.
  • Bang TH; Department of Agro-Environmental Sciences, Faculty of Agriculture, Kyushu University, Fukuoka, Japan.
  • Kondo R; Department of Agro-Environmental Sciences, Faculty of Agriculture, Kyushu University, Fukuoka, Japan.
  • Shimizu K; Department of Agro-Environmental Sciences, Faculty of Agriculture, Kyushu University, Fukuoka, Japan. Electronic address: shimizu@agr.kyushu-u.ac.jp.
Bioorg Med Chem ; 22(1): 211-20, 2014 Jan 01.
Article em En | MEDLINE | ID: mdl-24326278
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ácido Oleanólico / Inibidores da Topoisomerase I / Inibidores da Topoisomerase II / Antineoplásicos Idioma: En Ano de publicação: 2014 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ácido Oleanólico / Inibidores da Topoisomerase I / Inibidores da Topoisomerase II / Antineoplásicos Idioma: En Ano de publicação: 2014 Tipo de documento: Article