Construction of DNA-polymer hybrids using intercalation interactions.
Chem Commun (Camb)
; 50(11): 1338-40, 2014 Feb 09.
Article
em En
| MEDLINE
| ID: mdl-24346828
ABSTRACT
Reversible addition-fragmentation chain transfer (RAFT) polymerisation was used to produce a range of polymers terminated with an acridine group, which intercalates efficiently into dsDNA; the structure of the polymer determines the nature and strength of the interaction. Using a short 63 base pair dsDNA, discrete and well-defined DNA-polymer hybrid nanoparticles were formed, which were characterised by dynamic light scattering, small-angle X-ray scattering and atomic force microscopy.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Polímeros
/
Acridinas
/
DNA
/
Nanopartículas
/
Substâncias Intercalantes
Idioma:
En
Ano de publicação:
2014
Tipo de documento:
Article