Paraneoplastic disorders of the central and peripheral nervous systems.
Handb Clin Neurol
; 121: 1159-79, 2014.
Article
em En
| MEDLINE
| ID: mdl-24365410
ABSTRACT
Paraneoplatic neurologic syndromes (PNS) have been seminally defined as acute or subacute neurological syndromes resulting from nervous system dysfunction that is remote from the site of a malignant neoplasm or its metastases. However, in respect to our current understanding of their pathogenesis we may redefine these disorders as cancer-related dysimmune neurologic syndromes. We first deal with the epidemiology and the pathogenesis of PNS, then the different classic PNS are reviewed with clinical features according to the associated onconeuronal antibodies. Finally, therapeutic approaches are discussed.
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Base de dados:
MEDLINE
Assunto principal:
Neoplasias do Sistema Nervoso Periférico
/
Neoplasias do Sistema Nervoso Central
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Síndromes Paraneoplásicas do Sistema Nervoso
Idioma:
En
Ano de publicação:
2014
Tipo de documento:
Article