Potential role of subunit c of F0F1-ATPase and subunit c of storage body in the mitochondrial permeability transition. Effect of the phosphorylation status of subunit c on pore opening.

Azarashvili, Tamara; Odinokova, Irina; Bakunts, Anush; Ternovsky, Vadim; Krestinina, Olga; Tyynelä, Jaana; Saris, Nils-Erik Leo

Azarashvili, Tamara; Odinokova, Irina; Bakunts, Anush; Ternovsky, Vadim; Krestinina, Olga; Tyynelä, Jaana; Saris, Nils-Erik Leo.

Afiliação

Azarashvili T; Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Pushchino, Moscow Region, Russia; Institute of Biomedicine, Biochemistry and Developmental Biology, University of Helsinki, Helsinki, Finland. Electronic address: tamara.azarashvili@gmail.com.
Odinokova I; Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Pushchino, Moscow Region, Russia; Institute of Biomedicine, Biochemistry and Developmental Biology, University of Helsinki, Helsinki, Finland.
Bakunts A; Institute for Biological Instrumentation, Russian Academy of Sciences, Pushchino, Moscow Region, Russia; San Raffaele Scientific Institute, Milan, Italy.
Ternovsky V; Institute of Cell Biophysics, Russian Academy of Sciences, Pushchino, Moscow Region, Russia.
Krestinina O; Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Pushchino, Moscow Region, Russia.
Tyynelä J; Institute of Biomedicine, Biochemistry and Developmental Biology, University of Helsinki, Helsinki, Finland.
Saris NE; Institute of Biomedicine, Biochemistry and Developmental Biology, University of Helsinki, Helsinki, Finland; Department of Food and Environmental Sciences, University of Helsinki, P.O. Box 56, Viikki Biocenter 1, FIN-00014 Helsinki, Finland.

Cell Calcium ; 55(2): 69-77, 2014 Feb.

Article em En | MEDLINE | ID: mdl-24380588

Assuntos

Mitocôndrias Hepáticas/metabolismo; Proteínas de Transporte da Membrana Mitocondrial/metabolismo; ATPases Translocadoras de Prótons/metabolismo; Animais; Cálcio/metabolismo; Cálcio/farmacologia; Ciclosporina/farmacologia; Cinética; Bicamadas Lipídicas/química; Bicamadas Lipídicas/metabolismo; Masculino; Potencial da Membrana Mitocondrial/efeitos dos fármacos; Poro de Transição de Permeabilidade Mitocondrial; Dilatação Mitocondrial/efeitos dos fármacos; Fosforilação; Ligação Proteica; Subunidades Proteicas/isolamento & purificação; Subunidades Proteicas/metabolismo; Ratos; Ratos Wistar; Ovinos

Palavras-chave

Black-lipid membranes; F(0)F(1)-ATPase; Mitochondria; Permeability transition pore; Subunit c phosphorylation; [Ca(2+)]

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Mitocôndrias Hepáticas / ATPases Translocadoras de Prótons / Proteínas de Transporte da Membrana Mitocondrial Idioma: En Ano de publicação: 2014 Tipo de documento: Article

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