An expeditious synthetic approach towards the synthesis of Bis-Schiff bases (aldazines) using ultrasound.
Ultrason Sonochem
; 21(3): 1200-5, 2014 May.
Article
em En
| MEDLINE
| ID: mdl-24398059
ABSTRACT
Aldazines (Bis-Schiff bases) 1-24 were synthesized using aromatic aldehydes (heterocyclic and benzaldehydes) and hydrazine hydrate under reflux using conventional heating and/or via ultrasound irradiation using BiCl3 as catalyst. Ultrasonication conditions with cat. BiCl3 proved to be an effective, environmentally friendly synthetic procedure. This methodology is robust in the presence of electron donating and electron withdrawing groups affording desired products with high yields (>95%) in just a couple of minutes vs. hours using conventional heating.
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Base de dados:
MEDLINE
Assunto principal:
Bases de Schiff
/
Ultrassom
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Técnicas de Química Sintética
Idioma:
En
Ano de publicação:
2014
Tipo de documento:
Article