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Identification of a new epitope in uPAR as a target for the cancer therapeutic monoclonal antibody ATN-658, a structural homolog of the uPAR binding integrin CD11b (αM).
Xu, Xiang; Cai, Yuan; Wei, Ying; Donate, Fernando; Juarez, Jose; Parry, Graham; Chen, Liqing; Meehan, Edward J; Ahn, Richard W; Ugolkov, Andrey; Dubrovskyi, Oleksii; O'Halloran, Thomas V; Huang, Mingdong; Mazar, Andrew P.
Afiliação
  • Xu X; Division of Hemostasis and Thrombosis, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States of America.
  • Cai Y; Division of Hemostasis and Thrombosis, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States of America ; State Key Laboratory of Structural Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou, Fujian, C
  • Wei Y; Department of Medicine, University of California San Francisco, San Francisco, California, United States of America.
  • Donate F; Agensys, St. Santa Monica, California, United States of America.
  • Juarez J; GNF, San Diego, California, United States of America.
  • Parry G; Attenuon, San Diego, California, United States of America.
  • Chen L; Department of Chemistry, University of Alabama in Huntsville, Huntsville, Alabama, United States of America.
  • Meehan EJ; Department of Chemistry, University of Alabama in Huntsville, Huntsville, Alabama, United States of America.
  • Ahn RW; Department of Chemistry, Northwestern University, Evanston, Illinois, United States of America.
  • Ugolkov A; Chemistry of Life Processes Institute, Northwestern University, Evanston, Illinois, United States of America.
  • Dubrovskyi O; Chemistry of Life Processes Institute, Northwestern University, Evanston, Illinois, United States of America.
  • O'Halloran TV; Chemistry of Life Processes Institute, Northwestern University, Evanston, Illinois, United States of America ; Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Evanston, Illinois, United States of America ; Department of Molecular Biosciences, Northwestern University, Evanston,
  • Huang M; Division of Hemostasis and Thrombosis, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States of America.
  • Mazar AP; Chemistry of Life Processes Institute, Northwestern University, Evanston, Illinois, United States of America ; Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Evanston, Illinois, United States of America ; Department of Molecular Biosciences, Northwestern University, Evanston,
PLoS One ; 9(1): e85349, 2014.
Article em En | MEDLINE | ID: mdl-24465541
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Antígeno CD11b / Receptores de Ativador de Plasminogênio Tipo Uroquinase / Anticorpos Monoclonais / Epitopos Idioma: En Ano de publicação: 2014 Tipo de documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Antígeno CD11b / Receptores de Ativador de Plasminogênio Tipo Uroquinase / Anticorpos Monoclonais / Epitopos Idioma: En Ano de publicação: 2014 Tipo de documento: Article