[Effect of Jiangzhi Kangyanghua mixture on high-sensitivity C-reactive protein and vascular endothelial functions of hypertension patients].
Zhongguo Zhong Yao Za Zhi
; 38(20): 3583-6, 2013 Oct.
Article
em Zh
| MEDLINE
| ID: mdl-24490577
ABSTRACT
To observe the effect of Jiangzhikangyanghua Mixture on high-sensitivity CRP (hs-CRP) and vascular endothelial functions of essential hypertension (EH) patients. In this study, 72 cases of out-patients with EH were selected from department of cardiology of Wujin hospital of traditional Chinese Medicine, and randomly divided into the control group (n= 36, amlodipine 5 mg qd + valsartan 80 mg qd) and the test group (n =36 amlodipine 5 mg qd + valsartan 80 mg qd + Jiangzhikangyanghua mixture 20 mL tid). The contents of hs-CRP, ET-1 and NO were measured before and after treatment for two months. The result showed that the contents of hs-CRP, ET-1 in both groups reduced (P <0. 05) , while the test group show a more significant reduction than the control group (P <0. 05). After the treatment, the content of NO raised in both group, while the test group show a more significant increase than that of the control group (P <0. 05). This study indicated that Jiangzhi Kangyanghua mixture could reduce the contents of hs-CRP and ET-1 and raise NO of EH patients.
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Base de dados:
MEDLINE
Assunto principal:
Proteína C-Reativa
/
Medicamentos de Ervas Chinesas
/
Endotélio Vascular
/
Hipertensão
/
Anti-Hipertensivos
Idioma:
Zh
Ano de publicação:
2013
Tipo de documento:
Article