Binding interactions of hydroxylated polychlorinated biphenyls (OHPCBs) with human hydroxysteroid sulfotransferase hSULT2A1.

Ekuase, Edugie J; Lehmler, Hans-Joachim; Robertson, Larry W; Duffel, Michael W

Ekuase, Edugie J; Lehmler, Hans-Joachim; Robertson, Larry W; Duffel, Michael W.

Afiliação

Ekuase EJ; Department of Pharmaceutical Sciences and Experimental Therapeutics, College of Pharmacy, University of Iowa, Iowa City, IA 52242, United States.
Lehmler HJ; Department of Occupational and Environmental Health, College of Public Health, University of Iowa, Iowa City, IA 52242, United States.
Robertson LW; Department of Occupational and Environmental Health, College of Public Health, University of Iowa, Iowa City, IA 52242, United States.
Duffel MW; Department of Pharmaceutical Sciences and Experimental Therapeutics, College of Pharmacy, University of Iowa, Iowa City, IA 52242, United States. Electronic address: michael-duffel@uiowa.edu.

Chem Biol Interact ; 212: 56-64, 2014 Apr 05.

Article em En | MEDLINE | ID: mdl-24508592

Assuntos

Poluentes Ambientais/química; Poluentes Ambientais/metabolismo; Inibidores Enzimáticos/química; Inibidores Enzimáticos/metabolismo; Bifenilos Policlorados/química; Bifenilos Policlorados/metabolismo; Sulfotransferases/metabolismo; Animais; Desidroepiandrosterona/metabolismo; Poluentes Ambientais/farmacologia; Inibidores Enzimáticos/farmacologia; Humanos; Hidroxilação; Modelos Moleculares; Bifenilos Policlorados/farmacologia; Ligação Proteica; Conformação Proteica; Sulfotransferases/antagonistas & inibidores; Sulfotransferases/química

Palavras-chave

Hydroxylated polychlorinated biphenyl; OHPCB; PCB; Sulfotransferase; hSULT2A1

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sulfotransferases / Bifenilos Policlorados / Poluentes Ambientais / Inibidores Enzimáticos Idioma: En Ano de publicação: 2014 Tipo de documento: Article

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