Photophysicochemical behavior and antimicrobial activity of dihydroxosilicon tris(diaquaplatinum)octacarboxyphthalocyanine.
Spectrochim Acta A Mol Biomol Spectrosc
; 125: 147-53, 2014 May 05.
Article
em En
| MEDLINE
| ID: mdl-24534426
ABSTRACT
Platination of dihydroxosilicon octacarboxyphthalocyanine (OH)2SiOCPc was successfully carried out to give dihydroxosilicon tris(diaquaplatinum)octacarboxyphthalocyanine (OH)2SiOCPc(Pt)3 conjugate. Slight blue shifting of the absorption spectrum of (OH)2SiOCPc(Pt)3 was observed on conjugation with platinum. Comparative photophysicochemical behavior and antimicrobial photo-activities of (OH)2SiOCPc(Pt)3 conjugate with (OH)2SiOCPc or Pt nanoparticles revealed that the heavy atom, Pt on the periphery of the phthalocyanine significantly enhanced its singlet oxygen generation with a quantum yield of 0.56 obtained for the (OH)2SiOCPc(Pt)3 conjugate. The (OH)2SiOCPc(Pt)3 conjugate showed highest antimicrobial activity towards Candida albicans and Escherichia coli compared to (OH)2SiOCPc and Pt nanoparticles alone under illumination.
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Base de dados:
MEDLINE
Assunto principal:
Compostos Organoplatínicos
/
Luz
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Anti-Infecciosos
Idioma:
En
Ano de publicação:
2014
Tipo de documento:
Article