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Admixture mapping and subsequent fine-mapping suggests a biologically relevant and novel association on chromosome 11 for type 2 diabetes in African Americans.
Jeff, Janina M; Armstrong, Loren L; Ritchie, Marylyn D; Denny, Joshua C; Kho, Abel N; Basford, Melissa A; Wolf, Wendy A; Pacheco, Jennifer A; Li, Rongling; Chisholm, Rex L; Roden, Dan M; Hayes, M Geoffrey; Crawford, Dana C.
Afiliação
  • Jeff JM; Charles Bronfman Institute of Personalized Medicine, Icahn School of Medicine at Mount Sinai, Vanderbilt University, Nashville, Tennessee, United States of America.
  • Armstrong LL; Division of Endocrinology, Metabolism, and Molecular Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, United States of America.
  • Ritchie MD; Center for System Genomics, Department of Biochemistry and Molecular Biology, Pennsylvania State University, University Park, Pennsylvania, United States of America.
  • Denny JC; Department of Medicine, Division of Clinical Pharmacology,Vanderbilt University, Nashville, Tennessee, United States of America; Department of Biomedical Informatics, Vanderbilt University, Nashville, Tennessee, United States of America.
  • Kho AN; Division of General Internal Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, United States of America.
  • Basford MA; Office of Personalized Medicine, Vanderbilt University, Nashville, Tennessee, United States of America.
  • Wolf WA; Division of Genetics, Children's Hospital Boston, Boston, Massachusetts, United States of America.
  • Pacheco JA; Center for Genetic Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, United States of America.
  • Li R; Office of Population Genomics, National Human Genome Research Institute, Bethesda, Maryland, United States of America.
  • Chisholm RL; Center for Genetic Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, United States of America.
  • Roden DM; Department of Medicine, Division of Clinical Pharmacology,Vanderbilt University, Nashville, Tennessee, United States of America; Office of Personalized Medicine, Vanderbilt University, Nashville, Tennessee, United States of America; Department of Pharmacology, Vanderbilt University, Nashville, Tenne
  • Hayes MG; Division of Endocrinology, Metabolism, and Molecular Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, United States of America; Center for Genetic Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, United States of America.
  • Crawford DC; Center for Human Genetics Research, Vanderbilt University, Nashville, Tennessee, United States of America.
PLoS One ; 9(3): e86931, 2014.
Article em En | MEDLINE | ID: mdl-24595071
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Cromossomos Humanos Par 11 / Mapeamento Cromossômico / População Negra / Diabetes Mellitus Tipo 2 Idioma: En Ano de publicação: 2014 Tipo de documento: Article
Texto completo
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XML
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Cromossomos Humanos Par 11 / Mapeamento Cromossômico / População Negra / Diabetes Mellitus Tipo 2 Idioma: En Ano de publicação: 2014 Tipo de documento: Article