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A highly sensitive electrochemical genosensor based on Co-porphyrin-labelled DNA.
Grabowska, Iwona; Singleton, Daniel G; Stachyra, Anna; Góra-Sochacka, Anna; Sirko, Agnieszka; Zagórski-Ostoja, Wlodzimierz; Radecka, Hanna; Stulz, Eugen; Radecki, Jerzy.
Afiliação
  • Grabowska I; Institute of Animal Reproduction and Food Research, Polish Academy of Sciences, Tuwima 10, 10-747 Olsztyn, Poland. j.radecki@pan.olsztyn.pl.
Chem Commun (Camb) ; 50(32): 4196-9, 2014 Apr 25.
Article em En | MEDLINE | ID: mdl-24633340
ABSTRACT
We report the use of Co-porphyrins as electrochemical tags for a highly sensitive and selective genosensor. An avian influenza virus-based DNA sequence characteristic of H5N1 was detected at femtomolar levels from competing non-complementary sequences through hybridisation with the labeled DNA.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Porfirinas / DNA Viral / Técnicas Biossensoriais / Sondas de DNA / Eletroquímica / Virus da Influenza A Subtipo H5N1 Idioma: En Ano de publicação: 2014 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Porfirinas / DNA Viral / Técnicas Biossensoriais / Sondas de DNA / Eletroquímica / Virus da Influenza A Subtipo H5N1 Idioma: En Ano de publicação: 2014 Tipo de documento: Article