Mislocalization of the cell polarity protein scribble promotes mammary tumorigenesis and is associated with basal breast cancer.

Feigin, Michael E; Akshinthala, S Dipikaa; Araki, Kiyomi; Rosenberg, Avi Z; Muthuswamy, Lakshmi B; Martin, Bernard; Lehmann, Brian D; Berman, Hal K; Pietenpol, Jennifer A; Cardiff, Robert D; Muthuswamy, Senthil K

Feigin, Michael E; Akshinthala, S Dipikaa; Araki, Kiyomi; Rosenberg, Avi Z; Muthuswamy, Lakshmi B; Martin, Bernard; Lehmann, Brian D; Berman, Hal K; Pietenpol, Jennifer A; Cardiff, Robert D; Muthuswamy, Senthil K.

Afiliação

Feigin ME; Authors' Affiliations: Cold Spring Harbor Laboratory, Cold Spring Harbor, New York; Princess Margaret Cancer Center, Campbell Family Institute for Breast Cancer Research, Department of Medical Biophysics, University of Toronto; Ontario Institute for Cancer Research, Ontario, Canada; Center for Compa
Akshinthala SD; Authors' Affiliations: Cold Spring Harbor Laboratory, Cold Spring Harbor, New York; Princess Margaret Cancer Center, Campbell Family Institute for Breast Cancer Research, Department of Medical Biophysics, University of Toronto; Ontario Institute for Cancer Research, Ontario, Canada; Center for Compa
Araki K; Authors' Affiliations: Cold Spring Harbor Laboratory, Cold Spring Harbor, New York; Princess Margaret Cancer Center, Campbell Family Institute for Breast Cancer Research, Department of Medical Biophysics, University of Toronto; Ontario Institute for Cancer Research, Ontario, Canada; Center for Compa
Rosenberg AZ; Authors' Affiliations: Cold Spring Harbor Laboratory, Cold Spring Harbor, New York; Princess Margaret Cancer Center, Campbell Family Institute for Breast Cancer Research, Department of Medical Biophysics, University of Toronto; Ontario Institute for Cancer Research, Ontario, Canada; Center for Compa
Muthuswamy LB; Authors' Affiliations: Cold Spring Harbor Laboratory, Cold Spring Harbor, New York; Princess Margaret Cancer Center, Campbell Family Institute for Breast Cancer Research, Department of Medical Biophysics, University of Toronto; Ontario Institute for Cancer Research, Ontario, Canada; Center for Compa
Martin B; Authors' Affiliations: Cold Spring Harbor Laboratory, Cold Spring Harbor, New York; Princess Margaret Cancer Center, Campbell Family Institute for Breast Cancer Research, Department of Medical Biophysics, University of Toronto; Ontario Institute for Cancer Research, Ontario, Canada; Center for Compa
Lehmann BD; Authors' Affiliations: Cold Spring Harbor Laboratory, Cold Spring Harbor, New York; Princess Margaret Cancer Center, Campbell Family Institute for Breast Cancer Research, Department of Medical Biophysics, University of Toronto; Ontario Institute for Cancer Research, Ontario, Canada; Center for Compa
Berman HK; Authors' Affiliations: Cold Spring Harbor Laboratory, Cold Spring Harbor, New York; Princess Margaret Cancer Center, Campbell Family Institute for Breast Cancer Research, Department of Medical Biophysics, University of Toronto; Ontario Institute for Cancer Research, Ontario, Canada; Center for Compa
Pietenpol JA; Authors' Affiliations: Cold Spring Harbor Laboratory, Cold Spring Harbor, New York; Princess Margaret Cancer Center, Campbell Family Institute for Breast Cancer Research, Department of Medical Biophysics, University of Toronto; Ontario Institute for Cancer Research, Ontario, Canada; Center for Compa
Cardiff RD; Authors' Affiliations: Cold Spring Harbor Laboratory, Cold Spring Harbor, New York; Princess Margaret Cancer Center, Campbell Family Institute for Breast Cancer Research, Department of Medical Biophysics, University of Toronto; Ontario Institute for Cancer Research, Ontario, Canada; Center for Compa
Muthuswamy SK; Authors' Affiliations: Cold Spring Harbor Laboratory, Cold Spring Harbor, New York; Princess Margaret Cancer Center, Campbell Family Institute for Breast Cancer Research, Department of Medical Biophysics, University of Toronto; Ontario Institute for Cancer Research, Ontario, Canada; Center for Compa

Cancer Res ; 74(11): 3180-94, 2014 Jun 01.

Article em En | MEDLINE | ID: mdl-24662921

Assuntos

Neoplasias da Mama/genética; Neoplasias da Mama/patologia; Carcinogênese/genética; Carcinogênese/patologia; Polaridade Celular/genética; Proteínas de Membrana/genética; Proteínas de Membrana/metabolismo; Proteínas Supressoras de Tumor/genética; Proteínas Supressoras de Tumor/metabolismo; Animais; Neoplasias da Mama/metabolismo; Carcinogênese/metabolismo; Linhagem Celular; Linhagem Celular Tumoral; Classe I de Fosfatidilinositol 3-Quinases; Feminino; Expressão Gênica/genética; Células HEK293; Humanos; Camundongos; Camundongos Transgênicos; PTEN Fosfo-Hidrolase/genética; PTEN Fosfo-Hidrolase/metabolismo; Fosfatidilinositol 3-Quinases/genética; Fosfatidilinositol 3-Quinases/metabolismo; Proteínas Proto-Oncogênicas c-akt/genética; Proteínas Proto-Oncogênicas c-akt/metabolismo; Transdução de Sinais/genética; Serina-Treonina Quinases TOR/genética; Serina-Treonina Quinases TOR/metabolismo

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Polaridade Celular / Proteínas Supressoras de Tumor / Carcinogênese / Proteínas de Membrana Idioma: En Ano de publicação: 2014 Tipo de documento: Article

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