Molecular polymorphism of the ABO blood group: a study in Poland, Spain, and Andorra.
Am J Hum Biol
; 26(4): 556-8, 2014.
Article
em En
| MEDLINE
| ID: mdl-24677298
ABSTRACT
OBJECTIVES:
The main goal of this study is to increase knowledge on the molecular level of the ABO blood group system in Europe by providing data for Poland, Spain, and Andorra populations.METHODS:
A total of 172 oral scrapings samples from individuals of Polish origin, 108 peripheral blood samples of autochthonous individuals from the province of Zamora (Spain), and 81 peripheral blood samples from individuals with Andorran origin, were analyzed. Molecular characterization of the allelic variants was performed by the analysis of exons 6 and 7 of the ABO gene.RESULTS:
Seven common alleles were identified, namely A101, A102, A201, B101, O01, O02, and O03. Less common variants (O05, O09, O21, O26, O06, O11, and O12), were also detected.CONCLUSIONS:
The results obtained contribute to the knowledge of the molecular European ABO map, and are discussed in regard to the allelic frequency reported by other Caucasian and Asian populations.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Polimorfismo Genético
/
Sistema ABO de Grupos Sanguíneos
Idioma:
En
Ano de publicação:
2014
Tipo de documento:
Article