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Dioscin enhances methotrexate absorption by down-regulating MDR1 in vitro and in vivo.
Wang, Lijuan; Wang, Changyuan; Peng, Jinyong; Liu, Qi; Meng, Qiang; Sun, Huijun; Huo, Xiaokui; Sun, Pengyuan; Yang, Xiaobo; Zhen, Yuhong; Liu, Kexin.
Afiliação
  • Wang L; Department of Clinical Pharmacology, College of Pharmacy, Dalian Medical University, Dalian, Liaoning, PR China. Electronic address: jlwang1979@163.com.
  • Wang C; Department of Clinical Pharmacology, College of Pharmacy, Dalian Medical University, Dalian, Liaoning, PR China; Provincial Key Laboratory for Pharmacokinetics and Transport, Liaoning, Dalian Medical University, Dalian, Liaoning, PR China. Electronic address: wangcyuan@163.com.
  • Peng J; Department of Clinical Pharmacology, College of Pharmacy, Dalian Medical University, Dalian, Liaoning, PR China; Provincial Key Laboratory for Pharmacokinetics and Transport, Liaoning, Dalian Medical University, Dalian, Liaoning, PR China. Electronic address: jinyongpeng2005@163.com.
  • Liu Q; Department of Clinical Pharmacology, College of Pharmacy, Dalian Medical University, Dalian, Liaoning, PR China; Provincial Key Laboratory for Pharmacokinetics and Transport, Liaoning, Dalian Medical University, Dalian, Liaoning, PR China. Electronic address: llaqii@yahoo.com.cn.
  • Meng Q; Department of Clinical Pharmacology, College of Pharmacy, Dalian Medical University, Dalian, Liaoning, PR China; Provincial Key Laboratory for Pharmacokinetics and Transport, Liaoning, Dalian Medical University, Dalian, Liaoning, PR China. Electronic address: mengq531@yahoo.cn.
  • Sun H; Department of Clinical Pharmacology, College of Pharmacy, Dalian Medical University, Dalian, Liaoning, PR China; Provincial Key Laboratory for Pharmacokinetics and Transport, Liaoning, Dalian Medical University, Dalian, Liaoning, PR China. Electronic address: sunhuijun@hotmail.com.
  • Huo X; Department of Clinical Pharmacology, College of Pharmacy, Dalian Medical University, Dalian, Liaoning, PR China; Provincial Key Laboratory for Pharmacokinetics and Transport, Liaoning, Dalian Medical University, Dalian, Liaoning, PR China. Electronic address: huoxiaokui@163.com.
  • Sun P; Department of Clinical Pharmacology, College of Pharmacy, Dalian Medical University, Dalian, Liaoning, PR China; Provincial Key Laboratory for Pharmacokinetics and Transport, Liaoning, Dalian Medical University, Dalian, Liaoning, PR China. Electronic address: spfar1004@gmail.com.
  • Yang X; Department of Clinical Pharmacology, College of Pharmacy, Dalian Medical University, Dalian, Liaoning, PR China; Provincial Key Laboratory for Pharmacokinetics and Transport, Liaoning, Dalian Medical University, Dalian, Liaoning, PR China. Electronic address: bocai789770@163.com.
  • Zhen Y; Department of Clinical Pharmacology, College of Pharmacy, Dalian Medical University, Dalian, Liaoning, PR China; Provincial Key Laboratory for Pharmacokinetics and Transport, Liaoning, Dalian Medical University, Dalian, Liaoning, PR China. Electronic address: zhenyhwaner@yahoo.com.cn.
  • Liu K; Department of Clinical Pharmacology, College of Pharmacy, Dalian Medical University, Dalian, Liaoning, PR China; Provincial Key Laboratory for Pharmacokinetics and Transport, Liaoning, Dalian Medical University, Dalian, Liaoning, PR China. Electronic address: kexinliu@dlmedu.edu.cn.
Toxicol Appl Pharmacol ; 277(2): 146-54, 2014 Jun 01.
Article em En | MEDLINE | ID: mdl-24680847
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Metotrexato / Membro 1 da Subfamília B de Cassetes de Ligação de ATP / Subfamília B de Transportador de Cassetes de Ligação de ATP / Enterócitos / Diosgenina / Absorção Intestinal / Intestino Delgado / Antimetabólitos Antineoplásicos Idioma: En Ano de publicação: 2014 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Metotrexato / Membro 1 da Subfamília B de Cassetes de Ligação de ATP / Subfamília B de Transportador de Cassetes de Ligação de ATP / Enterócitos / Diosgenina / Absorção Intestinal / Intestino Delgado / Antimetabólitos Antineoplásicos Idioma: En Ano de publicação: 2014 Tipo de documento: Article