Skeletal metastases in 301 breast cancer patients: patient survival and complications after surgery.
Breast
; 23(3): 286-90, 2014 Jun.
Article
em En
| MEDLINE
| ID: mdl-24684891
ABSTRACT
The aim was to identify prognostic variables associated with survival in 301 breast cancer patients after surgical treatment of skeletal metastases. The study period was 1986-2012. The median age at surgery was 61 (interquartile-range [IQR] 52-70) years. The cumulative 1-, 2-, and 5-year survival after surgery was 45% (95% CI 39-51), 27% (22-32), and 8% (5-12), respectively. The median follow-up time was 1 (IQR 0.2-2) year. Age over 60 years (Hazard ratio [HR] 1.9) and hemoglobin levels <110 g/L (HR 2) increased the risk of death after surgery. Patients with impending fractures (HR 0.4) had a lower death rate. The overall neurological function in patients with spinal metastases improved after surgery (p < 0.001). The complication rate was 25%, including 14% re-operations. Survival data and analysis of complications of this large cohort of surgically treated breast cancer patients help to set appropriate expectations for the patients, families, and medical staff.
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MEDLINE
Assunto principal:
Complicações Pós-Operatórias
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Neoplasias Ósseas
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Hemoglobinas
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Expectativa de Vida
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Procedimentos Ortopédicos
Idioma:
En
Ano de publicação:
2014
Tipo de documento:
Article