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Preclinical characterization of BMS-791325, an allosteric inhibitor of hepatitis C Virus NS5B polymerase.
Lemm, Julie A; Liu, Mengping; Gentles, Robert G; Ding, Min; Voss, Stacey; Pelosi, Lenore A; Wang, Ying-Kai; Rigat, Karen L; Mosure, Kathleen W; Bender, John A; Knipe, Jay O; Colonno, Richard; Meanwell, Nicholas A; Kadow, John F; Santone, Kenneth S; Roberts, Susan B; Gao, Min.
Afiliação
  • Lemm JA; Virology, Bristol-Myers Squibb Research and Development, Wallingford, Connecticut, USA julie.lemm@bms.com.
  • Liu M; Virology, Bristol-Myers Squibb Research and Development, Wallingford, Connecticut, USA.
  • Gentles RG; Molecular Sciences and Candidate Optimization, Bristol-Myers Squibb Research and Development, Wallingford, Connecticut, USA.
  • Ding M; Molecular Sciences and Candidate Optimization, Bristol-Myers Squibb Research and Development, Wallingford, Connecticut, USA.
  • Voss S; Virology, Bristol-Myers Squibb Research and Development, Wallingford, Connecticut, USA.
  • Pelosi LA; Virology, Bristol-Myers Squibb Research and Development, Wallingford, Connecticut, USA.
  • Wang YK; Virology, Bristol-Myers Squibb Research and Development, Wallingford, Connecticut, USA.
  • Rigat KL; Virology, Bristol-Myers Squibb Research and Development, Wallingford, Connecticut, USA.
  • Mosure KW; Molecular Sciences and Candidate Optimization, Bristol-Myers Squibb Research and Development, Wallingford, Connecticut, USA.
  • Bender JA; Medicinal Chemistry, Bristol-Myers Squibb Research and Development, Wallingford, Connecticut, USA.
  • Knipe JO; Molecular Sciences and Candidate Optimization, Bristol-Myers Squibb Research and Development, Wallingford, Connecticut, USA.
  • Colonno R; Virology, Bristol-Myers Squibb Research and Development, Wallingford, Connecticut, USA.
  • Meanwell NA; Medicinal Chemistry, Bristol-Myers Squibb Research and Development, Wallingford, Connecticut, USA.
  • Kadow JF; Medicinal Chemistry, Bristol-Myers Squibb Research and Development, Wallingford, Connecticut, USA.
  • Santone KS; Molecular Sciences and Candidate Optimization, Bristol-Myers Squibb Research and Development, Wallingford, Connecticut, USA.
  • Roberts SB; Virology, Bristol-Myers Squibb Research and Development, Wallingford, Connecticut, USA.
  • Gao M; Virology, Bristol-Myers Squibb Research and Development, Wallingford, Connecticut, USA.
Antimicrob Agents Chemother ; 58(6): 3485-95, 2014 Jun.
Article em En | MEDLINE | ID: mdl-24733465
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Antivirais / Benzazepinas / Proteínas não Estruturais Virais / Hepacivirus / Indóis Idioma: En Ano de publicação: 2014 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Antivirais / Benzazepinas / Proteínas não Estruturais Virais / Hepacivirus / Indóis Idioma: En Ano de publicação: 2014 Tipo de documento: Article