Oral health and dental late adverse effects in children in remission from malignant disease. A pilot case-control study in Italian children.
Eur J Paediatr Dent
; 15(1): 45-50, 2014 Mar.
Article
em En
| MEDLINE
| ID: mdl-24745592
ABSTRACT
AIM:
To investigate with a reliable method the oral features in Italian patients in remission from cancer, highlighting the relationship with age at cancer therapy and to compare the data with healthy controls. MATERIALS ANDMETHODS:
Twenty five childhood cancer survivors treated under the age of 10 years with chemotherapy w/wo Haemopoietic Stem Cell Transplantation and/or head-neck Radiotherapy, in remission from cancer for at least 3 years, were examined for dental caries and enamel defects. To assess dental age and dental abnormalities a panoramic radiograph was taken. Patients were grouped according to age at cancer therapy (<3 years subgroup Y; 3.1-5 years subgroup M; >5 years subgroup O). A control group of 26 healthy children was included.RESULTS:
There was not a statistically significant difference in caries prevalence between the two groups. A statistically significant difference between the two groups was found for enamel defects, dental abnormalities and dental age. The chi-squared test revealed a relationship between age at therapy and specific dental abnormalities.CONCLUSION:
This study shows that cancer therapy may increase the risk of development of enamel defects and dental abnormalities, especially in children treated under the age of 3 years.
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Base de dados:
MEDLINE
Assunto principal:
Doenças Dentárias
/
Sobreviventes
/
Terapia Neoadjuvante
/
Neoplasias de Cabeça e Pescoço
Idioma:
En
Ano de publicação:
2014
Tipo de documento:
Article