Novel tartrate-derived guanidine-catalyzed highly enantio- and diastereoselective Michael addition of 3-substituted oxindoles to nitroolefins.

Zou, Liwei; Bao, Xiaoze; Ma, Yuanyuan; Song, Yuming; Qu, Jingping; Wang, Baomin

Zou, Liwei; Bao, Xiaoze; Ma, Yuanyuan; Song, Yuming; Qu, Jingping; Wang, Baomin.

Afiliação

Zou L; State Key Laboratory of Fine Chemicals, School of Pharmaceutical Science and Technology, Dalian University of Technology, Dalian 116024, P. R. China. bmwang@dlut.edu.cn.

Chem Commun (Camb) ; 50(43): 5760-2, 2014 Jun 01.

Article em En | MEDLINE | ID: mdl-24752728

ABSTRACT

ABSTRACT

The Michael addition of 3-substituted oxindoles to nitroolefins was catalyzed by a novel tartrate-derived guanidine in high yield with excellent diastereo- and enantioselectivity. This method showed an extraordinarily broad substrate scope in terms of both reaction partners.

Assuntos

Alcenos/química; Guanidina/química; Indóis/química; Nitrocompostos/química; Tartaratos/química; Catálise; Oxindóis; Estereoisomerismo; Especificidade por Substrato

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tartaratos / Guanidina / Alcenos / Indóis / Nitrocompostos Idioma: En Ano de publicação: 2014 Tipo de documento: Article

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