Human airway smooth muscle maintain in situ cell orientation and phenotype when cultured on aligned electrospun scaffolds.

Morris, G E; Bridge, J C; Eltboli, O M I; Lewis, M P; Knox, A J; Aylott, J W; Brightling, C E; Ghaemmaghami, A M; Rose, F R A J

Morris, G E; Bridge, J C; Eltboli, O M I; Lewis, M P; Knox, A J; Aylott, J W; Brightling, C E; Ghaemmaghami, A M; Rose, F R A J.

Afiliação

Morris GE; Division of Drug Delivery and Tissue Engineering, Centre for Biomolecular Sciences, School of Pharmacy, University of Nottingham, Nottingham, United Kingdom;
Bridge JC; Division of Drug Delivery and Tissue Engineering, Centre for Biomolecular Sciences, School of Pharmacy, University of Nottingham, Nottingham, United Kingdom;
Eltboli OM; NIHR Respiratory Biomedical Research Unit, University of Leicester, Leicester, United Kingdom;
Knox AJ; Division of Respiratory Medicine, School of Medicine, University of Nottingham, Nottingham, United Kingdom;
Aylott JW; Laboratory of Biophysics and Surface Analysis, School of Pharmacy, University of Nottingham, Nottingham, United Kingdom; and.
Brightling CE; NIHR Respiratory Biomedical Research Unit, University of Leicester, Leicester, United Kingdom;
Ghaemmaghami AM; Division of Immunology, School of Life Sciences, University of Nottingham, Nottingham, United Kingdom.
Rose FR; Division of Drug Delivery and Tissue Engineering, Centre for Biomolecular Sciences, School of Pharmacy, University of Nottingham, Nottingham, United Kingdom; felicity.rose@nottingham.ac.uk.

Am J Physiol Lung Cell Mol Physiol ; 307(1): L38-47, 2014 Jul 01.

Article em En | MEDLINE | ID: mdl-24793171

Assuntos

Adesão Celular/fisiologia; Músculo Liso/citologia; Miócitos de Músculo Liso/citologia; Polietilenotereftalatos/farmacologia; Engenharia Tecidual/métodos; Alicerces Teciduais; Materiais Biocompatíveis/farmacologia; Adesão Celular/efeitos dos fármacos; Técnicas de Cultura de Células; Proliferação de Células; Células Cultivadas; Microambiente Celular; Humanos; Pulmão/citologia; Modelos Biológicos; Nanofibras

Palavras-chave

airway smooth muscle; aligned fibers; electrospinning; in vitro model; tissue engineering

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Adesão Celular / Polietilenotereftalatos / Engenharia Tecidual / Miócitos de Músculo Liso / Alicerces Teciduais / Músculo Liso Idioma: En Ano de publicação: 2014 Tipo de documento: Article

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