Maternal protein restriction leads to pancreatic failure in offspring: role of misexpressed microRNA-375.

Dumortier, Olivier; Hinault, Charlotte; Gautier, Nadine; Patouraux, Stéphanie; Casamento, Virginie; Van Obberghen, Emmanuel

Dumortier, Olivier; Hinault, Charlotte; Gautier, Nadine; Patouraux, Stéphanie; Casamento, Virginie; Van Obberghen, Emmanuel.

Afiliação

Dumortier O; INSERM, U1081, Institute for Research on Cancer and Aging of Nice (IRCAN), Aging and Diabetes Team, Nice, France CNRS, UMR7284, IRCAN, Nice, France University of Nice Sophia Antipolis, Nice, France.
Hinault C; INSERM, U1081, Institute for Research on Cancer and Aging of Nice (IRCAN), Aging and Diabetes Team, Nice, France CNRS, UMR7284, IRCAN, Nice, France University of Nice Sophia Antipolis, Nice, France Clinical Chemistry Laboratory, University Hospital, Nice, France.
Gautier N; INSERM, U1081, Institute for Research on Cancer and Aging of Nice (IRCAN), Aging and Diabetes Team, Nice, France CNRS, UMR7284, IRCAN, Nice, France University of Nice Sophia Antipolis, Nice, France.
Patouraux S; Central Pathology Laboratory, University Hospital, Nice, France.
Casamento V; INSERM, U1081, Institute for Research on Cancer and Aging of Nice (IRCAN), Aging and Diabetes Team, Nice, France CNRS, UMR7284, IRCAN, Nice, France University of Nice Sophia Antipolis, Nice, France.
Van Obberghen E; INSERM, U1081, Institute for Research on Cancer and Aging of Nice (IRCAN), Aging and Diabetes Team, Nice, France CNRS, UMR7284, IRCAN, Nice, France University of Nice Sophia Antipolis, Nice, France Clinical Chemistry Laboratory, University Hospital, Nice, France vanobbeg@unice.fr.

Diabetes ; 63(10): 3416-27, 2014 Oct.

Article em En | MEDLINE | ID: mdl-24834976

Assuntos

MicroRNAs/metabolismo; Pâncreas/metabolismo; Efeitos Tardios da Exposição Pré-Natal/metabolismo; Deficiência de Proteína/metabolismo; Animais; Diabetes Mellitus Tipo 2/genética; Diabetes Mellitus Tipo 2/metabolismo; Diabetes Mellitus Tipo 2/patologia; Dieta com Restrição de Proteínas; Feminino; MicroRNAs/genética; Pâncreas/patologia; Gravidez; Efeitos Tardios da Exposição Pré-Natal/genética; Efeitos Tardios da Exposição Pré-Natal/patologia; Deficiência de Proteína/genética; Deficiência de Proteína/patologia; Ratos; Ratos Wistar

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pâncreas / Efeitos Tardios da Exposição Pré-Natal / Deficiência de Proteína / MicroRNAs Idioma: En Ano de publicação: 2014 Tipo de documento: Article

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