Catalytic and noncatalytic roles of the CtIP endonuclease in double-strand break end resection.

Makharashvili, Nodar; Tubbs, Anthony T; Yang, Soo-Hyun; Wang, Hailong; Barton, Olivia; Zhou, Yi; Deshpande, Rajashree A; Lee, Ji-Hoon; Lobrich, Markus; Sleckman, Barry P; Wu, Xiaohua; Paull, Tanya T

Makharashvili, Nodar; Tubbs, Anthony T; Yang, Soo-Hyun; Wang, Hailong; Barton, Olivia; Zhou, Yi; Deshpande, Rajashree A; Lee, Ji-Hoon; Lobrich, Markus; Sleckman, Barry P; Wu, Xiaohua; Paull, Tanya T.

Afiliação

Makharashvili N; The Howard Hughes Medical Institute and Department of Molecular Biosciences, Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, TX 78712, USA.
Tubbs AT; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA.
Yang SH; The Howard Hughes Medical Institute and Department of Molecular Biosciences, Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, TX 78712, USA.
Wang H; Department of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, CA 92037, USA.
Barton O; Radiation Biology and DNA Repair, Darmstadt University of Technology, 64287 Darmstadt, Germany.
Zhou Y; The Howard Hughes Medical Institute and Department of Molecular Biosciences, Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, TX 78712, USA.
Deshpande RA; The Howard Hughes Medical Institute and Department of Molecular Biosciences, Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, TX 78712, USA.
Lee JH; The Howard Hughes Medical Institute and Department of Molecular Biosciences, Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, TX 78712, USA.
Lobrich M; Radiation Biology and DNA Repair, Darmstadt University of Technology, 64287 Darmstadt, Germany.
Sleckman BP; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA.
Wu X; Department of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, CA 92037, USA.
Paull TT; The Howard Hughes Medical Institute and Department of Molecular Biosciences, Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, TX 78712, USA. Electronic address: tpaull@utexas.edu.

Mol Cell ; 54(6): 1022-1033, 2014 Jun 19.

Article em En | MEDLINE | ID: mdl-24837676

Assuntos

Proteínas de Transporte/metabolismo; Quebras de DNA de Cadeia Dupla; Reparo do DNA por Junção de Extremidades/genética; Endonucleases/metabolismo; Proteínas Nucleares/metabolismo; Reparo de DNA por Recombinação/genética; Sítios de Ligação/genética; Proteínas de Transporte/genética; Catálise; Linhagem Celular; Sobrevivência Celular/genética; DNA/genética; Proteínas de Ligação a DNA/genética; Endodesoxirribonucleases; Endonucleases/genética; Humanos; Proteínas Nucleares/genética; Fosforilação/genética; Processamento de Proteína Pós-Traducional/genética; Radiação Ionizante; Recombinação Genética

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Nucleares / Proteínas de Transporte / Endonucleases / Quebras de DNA de Cadeia Dupla / Reparo do DNA por Junção de Extremidades / Reparo de DNA por Recombinação Idioma: En Ano de publicação: 2014 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google