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Chronic administration of cholesterol oximes in mice increases transcription of cytoprotective genes and improves transcriptome alterations induced by alpha-synuclein overexpression in nigrostriatal dopaminergic neurons.
Richter, Franziska; Gao, Fuying; Medvedeva, Vera; Lee, Patrick; Bove, Nicholas; Fleming, Sheila M; Michaud, Magali; Lemesre, Vincent; Patassini, Stefano; De La Rosa, Krystal; Mulligan, Caitlin K; Sioshansi, Pedrom C; Zhu, Chunni; Coppola, Giovanni; Bordet, Thierry; Pruss, Rebecca M; Chesselet, Marie-Françoise.
Afiliação
  • Richter F; Department of Neurology, The David Geffen School of Medicine at UCLA, 710 Westwood Plaza, Los Angeles, CA 90095-1769, USA.
  • Gao F; Department of Psychiatry, Semel Institute for Neuroscience and Human Behavior, The David Geffen School of Medicine at UCLA, 710 Westwood Plaza, Los Angeles, CA 90095-1769, USA.
  • Medvedeva V; Department of Neurology, The David Geffen School of Medicine at UCLA, 710 Westwood Plaza, Los Angeles, CA 90095-1769, USA.
  • Lee P; Department of Neurology, The David Geffen School of Medicine at UCLA, 710 Westwood Plaza, Los Angeles, CA 90095-1769, USA.
  • Bove N; Department of Neurology, The David Geffen School of Medicine at UCLA, 710 Westwood Plaza, Los Angeles, CA 90095-1769, USA.
  • Fleming SM; Department of Neurology, The David Geffen School of Medicine at UCLA, 710 Westwood Plaza, Los Angeles, CA 90095-1769, USA.
  • Michaud M; Trophos S.A. Parc Scientifique de Luminy, Case 931, 13288 Marseille Cedex 9, France.
  • Lemesre V; Department of Neurology, The David Geffen School of Medicine at UCLA, 710 Westwood Plaza, Los Angeles, CA 90095-1769, USA.
  • Patassini S; Department of Neurology, The David Geffen School of Medicine at UCLA, 710 Westwood Plaza, Los Angeles, CA 90095-1769, USA.
  • De La Rosa K; Department of Neurology, The David Geffen School of Medicine at UCLA, 710 Westwood Plaza, Los Angeles, CA 90095-1769, USA.
  • Mulligan CK; Department of Neurology, The David Geffen School of Medicine at UCLA, 710 Westwood Plaza, Los Angeles, CA 90095-1769, USA.
  • Sioshansi PC; Department of Neurology, The David Geffen School of Medicine at UCLA, 710 Westwood Plaza, Los Angeles, CA 90095-1769, USA.
  • Zhu C; Department of Neurology, The David Geffen School of Medicine at UCLA, 710 Westwood Plaza, Los Angeles, CA 90095-1769, USA.
  • Coppola G; Department of Neurology, The David Geffen School of Medicine at UCLA, 710 Westwood Plaza, Los Angeles, CA 90095-1769, USA; Department of Psychiatry, Semel Institute for Neuroscience and Human Behavior, The David Geffen School of Medicine at UCLA, 710 Westwood Plaza, Los Angeles, CA 90095-1769, USA.
  • Bordet T; Trophos S.A. Parc Scientifique de Luminy, Case 931, 13288 Marseille Cedex 9, France.
  • Pruss RM; Trophos S.A. Parc Scientifique de Luminy, Case 931, 13288 Marseille Cedex 9, France.
  • Chesselet MF; Department of Neurology, The David Geffen School of Medicine at UCLA, 710 Westwood Plaza, Los Angeles, CA 90095-1769, USA. Electronic address: mchesselet@mednet.ucla.edu.
Neurobiol Dis ; 69: 263-75, 2014 Sep.
Article em En | MEDLINE | ID: mdl-24844147
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Oximas / Secoesteroides / Encéfalo / Colestenonas / Fármacos Neuroprotetores / Alfa-Sinucleína / Neurônios Dopaminérgicos Idioma: En Ano de publicação: 2014 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Oximas / Secoesteroides / Encéfalo / Colestenonas / Fármacos Neuroprotetores / Alfa-Sinucleína / Neurônios Dopaminérgicos Idioma: En Ano de publicação: 2014 Tipo de documento: Article