Immunization of rabbits with highly purified, soluble, trimeric human immunodeficiency virus type 1 envelope glycoprotein induces a vigorous B cell response and broadly cross-reactive neutralization.

Quinnan, Gerald V; Onabajo, Olusegun; Zhang, Pengfei; Yan, Lianying; Mattapallil, Joseph J; Zhang, Zhiqiang; Dong, Ming; Lu, Min; Montefiori, David; LaBranche, Celia; Broder, Christopher C

Quinnan, Gerald V; Onabajo, Olusegun; Zhang, Pengfei; Yan, Lianying; Mattapallil, Joseph J; Zhang, Zhiqiang; Dong, Ming; Lu, Min; Montefiori, David; LaBranche, Celia; Broder, Christopher C.

Afiliação

Quinnan GV; Department of Preventive Medicine and Biometrics, Uniformed Services University of the Health Sciences, Bethesda, Maryland, United States of America.
Onabajo O; Department of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, Maryland, United States of America.
Zhang P; Department of Preventive Medicine and Biometrics, Uniformed Services University of the Health Sciences, Bethesda, Maryland, United States of America.
Yan L; Department of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, Maryland, United States of America.
Mattapallil JJ; Department of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, Maryland, United States of America.
Zhang Z; Department of Preventive Medicine and Biometrics, Uniformed Services University of the Health Sciences, Bethesda, Maryland, United States of America.
Dong M; Department of Preventive Medicine and Biometrics, Uniformed Services University of the Health Sciences, Bethesda, Maryland, United States of America.
Lu M; Department of Microbiology and Molecular Genetics, Public Health Research Institute, New Jersey Medical School, Newark, New Jersey, United States of America.
Montefiori D; Department of Surgery, Duke University Medical Center, Durham, North Carolina, United States of America.
LaBranche C; Department of Surgery, Duke University Medical Center, Durham, North Carolina, United States of America.
Broder CC; Department of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, Maryland, United States of America.

PLoS One ; 9(5): e98060, 2014.

Article em En | MEDLINE | ID: mdl-24846288

Assuntos

Anticorpos Neutralizantes/imunologia; Formação de Anticorpos/imunologia; Linfócitos B/imunologia; Reações Cruzadas/imunologia; Anticorpos Anti-HIV/imunologia; Imunização; Produtos do Gene env do Vírus da Imunodeficiência Humana/imunologia; Adjuvantes Imunológicos; Animais; Linfócitos B/metabolismo; Epitopos de Linfócito B/imunologia; Antígenos HIV/imunologia; Humanos; Linfonodos/imunologia; Linfonodos/metabolismo; Testes de Neutralização; Ligação Proteica; Multimerização Proteica; Coelhos; Receptores CCR5/metabolismo; Baço/imunologia; Baço/metabolismo; Produtos do Gene env do Vírus da Imunodeficiência Humana/química; Produtos do Gene env do Vírus da Imunodeficiência Humana/metabolismo

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Linfócitos B / Anticorpos Anti-HIV / Imunização / Reações Cruzadas / Produtos do Gene env do Vírus da Imunodeficiência Humana / Anticorpos Neutralizantes / Formação de Anticorpos Idioma: En Ano de publicação: 2014 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google