Aberrant DNA hypermethylation of SDHC: a novel mechanism of tumor development in Carney triad.

Haller, Florian; Moskalev, Evgeny A; Faucz, Fabio R; Barthelmeß, Sarah; Wiemann, Stefan; Bieg, Matthias; Assie, Guillaume; Bertherat, Jerome; Schaefer, Inga-Marie; Otto, Claudia; Rattenberry, Eleanor; Maher, Eamonn R; Ströbel, Philipp; Werner, Martin; Carney, J Aidan; Hartmann, Arndt; Stratakis, Constantine A; Agaimy, Abbas

Haller, Florian; Moskalev, Evgeny A; Faucz, Fabio R; Barthelmeß, Sarah; Wiemann, Stefan; Bieg, Matthias; Assie, Guillaume; Bertherat, Jerome; Schaefer, Inga-Marie; Otto, Claudia; Rattenberry, Eleanor; Maher, Eamonn R; Ströbel, Philipp; Werner, Martin; Carney, J Aidan; Hartmann, Arndt; Stratakis, Constantine A; Agaimy, Abbas.

Afiliação

Haller F; Institute of PathologyUniversity Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Krankenhausstraße 8-10, D-91054 Erlangen, GermanyProgram on Developmental Endocrinology and GeneticsEunice Kennedy Shriver National Institute of Child Health and Human Development, National Institu
Moskalev EA; Institute of PathologyUniversity Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Krankenhausstraße 8-10, D-91054 Erlangen, GermanyProgram on Developmental Endocrinology and GeneticsEunice Kennedy Shriver National Institute of Child Health and Human Development, National Institu
Faucz FR; Institute of PathologyUniversity Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Krankenhausstraße 8-10, D-91054 Erlangen, GermanyProgram on Developmental Endocrinology and GeneticsEunice Kennedy Shriver National Institute of Child Health and Human Development, National Institu
Barthelmeß S; Institute of PathologyUniversity Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Krankenhausstraße 8-10, D-91054 Erlangen, GermanyProgram on Developmental Endocrinology and GeneticsEunice Kennedy Shriver National Institute of Child Health and Human Development, National Institu
Wiemann S; Institute of PathologyUniversity Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Krankenhausstraße 8-10, D-91054 Erlangen, GermanyProgram on Developmental Endocrinology and GeneticsEunice Kennedy Shriver National Institute of Child Health and Human Development, National Institu
Bieg M; Institute of PathologyUniversity Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Krankenhausstraße 8-10, D-91054 Erlangen, GermanyProgram on Developmental Endocrinology and GeneticsEunice Kennedy Shriver National Institute of Child Health and Human Development, National Institu
Assie G; Institute of PathologyUniversity Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Krankenhausstraße 8-10, D-91054 Erlangen, GermanyProgram on Developmental Endocrinology and GeneticsEunice Kennedy Shriver National Institute of Child Health and Human Development, National Institu
Bertherat J; Institute of PathologyUniversity Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Krankenhausstraße 8-10, D-91054 Erlangen, GermanyProgram on Developmental Endocrinology and GeneticsEunice Kennedy Shriver National Institute of Child Health and Human Development, National Institu
Schaefer IM; Institute of PathologyUniversity Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Krankenhausstraße 8-10, D-91054 Erlangen, GermanyProgram on Developmental Endocrinology and GeneticsEunice Kennedy Shriver National Institute of Child Health and Human Development, National Institu
Otto C; Institute of PathologyUniversity Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Krankenhausstraße 8-10, D-91054 Erlangen, GermanyProgram on Developmental Endocrinology and GeneticsEunice Kennedy Shriver National Institute of Child Health and Human Development, National Institu
Rattenberry E; Institute of PathologyUniversity Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Krankenhausstraße 8-10, D-91054 Erlangen, GermanyProgram on Developmental Endocrinology and GeneticsEunice Kennedy Shriver National Institute of Child Health and Human Development, National Institu
Maher ER; Institute of PathologyUniversity Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Krankenhausstraße 8-10, D-91054 Erlangen, GermanyProgram on Developmental Endocrinology and GeneticsEunice Kennedy Shriver National Institute of Child Health and Human Development, National Institu
Ströbel P; Institute of PathologyUniversity Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Krankenhausstraße 8-10, D-91054 Erlangen, GermanyProgram on Developmental Endocrinology and GeneticsEunice Kennedy Shriver National Institute of Child Health and Human Development, National Institu
Werner M; Institute of PathologyUniversity Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Krankenhausstraße 8-10, D-91054 Erlangen, GermanyProgram on Developmental Endocrinology and GeneticsEunice Kennedy Shriver National Institute of Child Health and Human Development, National Institu
Carney JA; Institute of PathologyUniversity Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Krankenhausstraße 8-10, D-91054 Erlangen, GermanyProgram on Developmental Endocrinology and GeneticsEunice Kennedy Shriver National Institute of Child Health and Human Development, National Institu
Hartmann A; Institute of PathologyUniversity Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Krankenhausstraße 8-10, D-91054 Erlangen, GermanyProgram on Developmental Endocrinology and GeneticsEunice Kennedy Shriver National Institute of Child Health and Human Development, National Institu
Stratakis CA; Institute of PathologyUniversity Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Krankenhausstraße 8-10, D-91054 Erlangen, GermanyProgram on Developmental Endocrinology and GeneticsEunice Kennedy Shriver National Institute of Child Health and Human Development, National Institu
Agaimy A; Institute of PathologyUniversity Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Krankenhausstraße 8-10, D-91054 Erlangen, GermanyProgram on Developmental Endocrinology and GeneticsEunice Kennedy Shriver National Institute of Child Health and Human Development, National Institu

Endocr Relat Cancer ; 21(4): 567-77, 2014 Aug.

Article em En | MEDLINE | ID: mdl-24859990

Assuntos

Condroma/genética; Metilação de DNA; Leiomiossarcoma/genética; Neoplasias Pulmonares/genética; Proteínas de Membrana/genética; Paraganglioma Extrassuprarrenal/genética; Neoplasias Gástricas/genética; Adolescente; Adulto; Condroma/metabolismo; Ilhas de CpG; Regulação para Baixo; Epigênese Genética; Feminino; Humanos; Leiomiossarcoma/metabolismo; Neoplasias Pulmonares/metabolismo; Proteínas de Membrana/metabolismo; Pessoa de Meia-Idade; Mutação; Paraganglioma Extrassuprarrenal/metabolismo; Neoplasias Gástricas/metabolismo; Adulto Jovem

Palavras-chave

Carney triad; GIST; SDH complex; SDHC; paraganglioma

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Gástricas / Condroma / Paraganglioma Extrassuprarrenal / Metilação de DNA / Leiomiossarcoma / Neoplasias Pulmonares / Proteínas de Membrana Idioma: En Ano de publicação: 2014 Tipo de documento: Article

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