Generation of poly(N-vinylpyrrolidone) nanofibres using pressurised gyration.
Mater Sci Eng C Mater Biol Appl
; 39: 168-76, 2014 Jun 01.
Article
em En
| MEDLINE
| ID: mdl-24863213
ABSTRACT
The ability to generate nanofibres useful for biomedical applications at bench and at a larger scale is a significant manufacturing challenge. In this study, we demonstrate that it is possible to generate nanofibre meshes of poly(N-vinylpyrrolidone) (PVP) using pressurised gyration. The effects of altering polymer molecular weight and concentration on fibre morphology and size have been investigated, with identification of minimum values for both parameters for successful fibre fabrication. In addition, we note that changing the molecular weight may result in changes to the Fourier Transform Infrared (FTIR) spectra associated with changes in fibre intramolecular bond strength and arrangement. Overall the study has demonstrated that pressure gyration represents a feasible means of producing nanofibres (470-970nm) on a scale commensurate with commercial viability and have identified key parameters that influence mesh structure.
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Base de dados:
MEDLINE
Assunto principal:
Polímeros
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Pirrolidinonas
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Nanofibras
Idioma:
En
Ano de publicação:
2014
Tipo de documento:
Article