Safety and efficacy of filtered sunlight in treatment of jaundice in African neonates.
Pediatrics
; 133(6): e1568-74, 2014 Jun.
Article
em En
| MEDLINE
| ID: mdl-24864170
ABSTRACT
OBJECTIVES:
Evaluate safety and efficacy of filtered-sunlight phototherapy (FS-PT).METHODS:
Term/late preterm infants #14 days old with clinically significant jaundice, assessed by total bilirubin (TB) levels, were recruited from a maternity hospital in Lagos, Nigeria. Sunlight was filtered with commercial window-tinting films that remove most UV and significant levels of infrared light and transmit effective levels of therapeutic blue light. After placing infants under an FS-PT canopy, hourly measurements of axillary temperatures, monitoring for sunburn, dehydration, and irradiances of filtered sunlight were performed. Treatment was deemed safe and efficacious if infants were able to stay in FS-PT for $5 hours and rate of rise of TB was ,0.2 mg/dL/h for infants #72 hours of age or TB decreased for infants .72 hours of age.RESULTS:
A total of 227 infants received 258 days of FS-PT. No infant developed sunburn or dehydration. On 85 (33%) of 258 treatment days, infants were removed briefly from FS-PT due to minor temperature-related adverse events. No infant met study exit criteria. FS-PT was efficacious in 92% (181/197) of evaluable treatment days. Mean 6 SD TB change was 0.06 6 0.19 mg/dL/h. The mean 6 SD (range) irradiance of FS-PT was 38 6 22 (2115) mW/cm2/nm, measured by the BiliBlanket Meter II.CONCLUSIONS:
With appropriate monitoring, filtered sunlight is a novel, practical, and inexpensive method of PT that potentially offers safe and efficacious treatment strategy for management of neonatal jaundice in tropical countries where conventional PT treatment is not available.
Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Negro ou Afro-Americano
/
Países em Desenvolvimento
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Helioterapia
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Doenças do Prematuro
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Icterícia Neonatal
Idioma:
En
Ano de publicação:
2014
Tipo de documento:
Article