MRI displays involvement of the temporalis muscle and the deep temporal artery in patients with giant cell arteritis.
Eur Radiol
; 24(11): 2971-9, 2014 Nov.
Article
em En
| MEDLINE
| ID: mdl-24895039
ABSTRACT
PURPOSE:
To assess deep temporal artery and temporalis muscle involvement in patients with giant cell arteritis (GCA). MATERIAL ANDMETHODS:
Ninety-nine patients who received magnetic resonance imaging (MRI) and superficial temporal artery biopsy (TAB) were included in this study. Patients with positive TAB (n = 61) were defined as GCA patients, those with negative TAB (n = 38) as the GCA-negative reference group. Contrast-enhanced T1w-images were acquired utilizing 1.5 T and 3 T MRI. Two radiologists assessed the images. Mural contrast-hyperenhancement and wall thickening of the deep temporal artery and hyperenhancement of the muscle were defined as inflammation. MRI results were correlated with jaw claudication in 70 patients.RESULTS:
The two observers found temporalis muscle involvement in 19.7 % (n = 12) and 21.3 % (n = 13) of GCA patients. It occurred bilaterally in 100 %. Specificities were 92/97 % and sensitivities were 20/21 %. Deep temporal artery involvement was found in 34.4 % (n = 21) and 49.2 % (n = 30) and occurred bilaterally in 80/90.5 %. Specificities were 84/95 % and sensitivities were 34/49 %. Both structures were affected simultaneously in 18/21.3 %. Jaw claudication correlated moderately with inflammation of the temporalis muscle (r = 0.31; p < 0.05) and the deep temporal artery (r = 0.38; p = 0.01).CONCLUSION:
MRI visualizes changes in the temporalis muscle and the deep temporal artery in GCA. Moderate correlation of clinical symptoms with MRI results was observed. KEY POINTS ⢠Approximately 20 % of GCA patients presented with temporalis muscle inflammation. ⢠A total of 34-49 % of GCA patients presented with vasculitis of the deep temporal artery. ⢠In approximately 20 % of GCA patients, both structures were simultaneously involved. ⢠Involvement of both structures correlated moderately with presence of jaw claudication. ⢠MRI is a suitable tool for the assessment of vasculitis and muscle inflammation.
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Base de dados:
MEDLINE
Assunto principal:
Artérias Temporais
/
Arterite de Células Gigantes
/
Músculo Temporal
/
Imageamento por Ressonância Magnética
Idioma:
En
Ano de publicação:
2014
Tipo de documento:
Article