Early diagnosis of colorectal cancer in rats with DMH induced carcinogenesis by means of urine autofluorescence analysis.
Photochem Photobiol
; 90(3): 682-5, 2014.
Article
em En
| MEDLINE
| ID: mdl-24918239
ABSTRACT
Cancer is one of the most highlighted topics of current research. Early detection of this disease allows more effective therapy, hence higher chance of cure. Application of fluorescence spectral techniques into oncological diagnostic is one of the potential alternatives. Chemically induced carcinogenesis in rats is widely used model for exploration of various aspects of colorectal cancer. This study shows value of discriminate analysis of urine fluorescent fingerprint between healthy control group of rats and those with dimethylhydrazine induced early lesions of colorectal cancer. Using fluorescence spectroscopy, significant difference (P < 0.05) between both of group was achieved.
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Base de dados:
MEDLINE
Assunto principal:
Urina
/
Carcinógenos
/
Neoplasias Colorretais
/
Dimetilidrazinas
Idioma:
En
Ano de publicação:
2014
Tipo de documento:
Article