Population-based comparison of prognostic factors in invasive micropapillary and invasive ductal carcinoma of the breast.
Br J Cancer
; 111(3): 619-22, 2014 Jul 29.
Article
em En
| MEDLINE
| ID: mdl-24921921
ABSTRACT
BACKGROUND:
Invasive micropapillary carcinoma (IMPC) is a variant of breast carcinoma with a higher propensity for lymph node metastases compared with invasive ductal carcinoma (IDC).METHODS:
Retrospective analysis of 636 IMPC and 297 735 IDC cases in the Surveillance, Epidemiology and End RESULTS database comparing disease-specific survival (DSS) and overall survival (OS) between IMPC and IDC.RESULTS:
A higher percentage of IMPC cases (52.0%) had nodal metastases compared with IDC cases (34.6%). The 5-year DSS and OS for IMPC was 91.8% and 82.9%, respectively compared with 88.6% and 80.5% for IDC, respectively. For both IMPC and IDC, oestrogen-receptor positivity was associated with better survival, while having four or more positive lymph nodes or larger tumour size correlated with worse survival. Radiotherapy provided a survival benefit for both histological types.CONCLUSIONS:
Despite IMPC's higher propensity for lymph node metastasis, IMPC has DSS and OS that compare favourably with IDC.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Neoplasias da Mama
/
Carcinoma Papilar
/
Carcinoma Ductal de Mama
Idioma:
En
Ano de publicação:
2014
Tipo de documento:
Article