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Synthetic lethality in ATM-deficient RAD50-mutant tumors underlies outlier response to cancer therapy.
Al-Ahmadie, Hikmat; Iyer, Gopa; Hohl, Marcel; Asthana, Saurabh; Inagaki, Akiko; Schultz, Nikolaus; Hanrahan, Aphrothiti J; Scott, Sasinya N; Brannon, A Rose; McDermott, Gregory C; Pirun, Mono; Ostrovnaya, Irina; Kim, Philip; Socci, Nicholas D; Viale, Agnes; Schwartz, Gary K; Reuter, Victor; Bochner, Bernard H; Rosenberg, Jonathan E; Bajorin, Dean F; Berger, Michael F; Petrini, John H J; Solit, David B; Taylor, Barry S.
Afiliação
  • Al-Ahmadie H; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Iyer G; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York. Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York. Department of Medicine, Weill Cornell Medical College, New York, New York.
  • Hohl M; Molecular Biology Program, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Asthana S; Department of Medicine, University of California, San Francisco, California. Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California.
  • Inagaki A; Molecular Biology Program, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Schultz N; Computational Biology Program, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Hanrahan AJ; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Scott SN; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Brannon AR; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York.
  • McDermott GC; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Pirun M; Bioinformatics Core Laboratory, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Ostrovnaya I; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Kim P; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York. Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Socci ND; Bioinformatics Core Laboratory, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Viale A; Genomics Core Laboratory, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Schwartz GK; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Reuter V; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Bochner BH; Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Rosenberg JE; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York. Department of Medicine, Weill Cornell Medical College, New York, New York.
  • Bajorin DF; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York. Department of Medicine, Weill Cornell Medical College, New York, New York.
  • Berger MF; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York. Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Petrini JH; Molecular Biology Program, Memorial Sloan Kettering Cancer Center, New York, New York. taylorb@mskcc.org petrinij@mskcc.org solitd@mskcc.org.
  • Solit DB; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York. Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York. Department of Medicine, Weill Cornell Medical College, New York, New York. taylorb@mskcc.org petrinij@mskcc.org sol
  • Taylor BS; Department of Medicine, University of California, San Francisco, California. Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California. Department of Epidemiology and Biostatistics, University of California, San Francisco, California. taylorb@mskcc.org petr
Cancer Discov ; 4(9): 1014-21, 2014 Sep.
Article em En | MEDLINE | ID: mdl-24934408
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Enzimas Reparadoras do DNA / Proteínas de Ligação a DNA / Proteínas Mutadas de Ataxia Telangiectasia / Mutação / Neoplasias Idioma: En Ano de publicação: 2014 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Enzimas Reparadoras do DNA / Proteínas de Ligação a DNA / Proteínas Mutadas de Ataxia Telangiectasia / Mutação / Neoplasias Idioma: En Ano de publicação: 2014 Tipo de documento: Article