Promiscuity of Exiguobacterium sp. AT1b o-succinylbenzoate synthase illustrates evolutionary transitions in the OSBS family.

Brizendine, Ashley M; Odokonyero, Denis; McMillan, Andrew W; Zhu, Mingzhao; Hull, Ken; Romo, Daniel; Glasner, Margaret E

Brizendine, Ashley M; Odokonyero, Denis; McMillan, Andrew W; Zhu, Mingzhao; Hull, Ken; Romo, Daniel; Glasner, Margaret E.

Afiliação

Brizendine AM; Department of Biochemistry and Biophysics, Texas A&M University, 2128 TAMU, College Station, TX 77843-2128, United States. Electronic address: ashleybrizendine@neo.tamu.edu.
Odokonyero D; Department of Biochemistry and Biophysics, Texas A&M University, 2128 TAMU, College Station, TX 77843-2128, United States. Electronic address: denis.odokos@gmail.com.
McMillan AW; Department of Biochemistry and Biophysics, Texas A&M University, 2128 TAMU, College Station, TX 77843-2128, United States. Electronic address: amcmillan@tamu.edu.
Zhu M; Natural Products LINCHPIN Laboratory, Texas A&M University, 3255 TAMU, College Station, TX 77840, United States. Electronic address: mingzhao.zhu@mail.chem.tamu.edu.
Hull K; Natural Products LINCHPIN Laboratory, Texas A&M University, 3255 TAMU, College Station, TX 77840, United States. Electronic address: ken.hull@chem.tamu.edu.
Romo D; Natural Products LINCHPIN Laboratory, Texas A&M University, 3255 TAMU, College Station, TX 77840, United States; Department of Chemistry, Texas A&M University, 3255 TAMU, College Station, TX 77840, United States. Electronic address: romo@chem.tamu.edu.
Glasner ME; Department of Biochemistry and Biophysics, Texas A&M University, 2128 TAMU, College Station, TX 77843-2128, United States. Electronic address: margy.glasner@tamu.edu.

Biochem Biophys Res Commun ; 450(1): 679-84, 2014 Jul 18.

Article em En | MEDLINE | ID: mdl-24937446

Assuntos

Bacillales/enzimologia; Bacillales/genética; Carbono-Carbono Liases/química; Carbono-Carbono Liases/genética; Evolução Molecular; Sequência de Bases; Sítios de Ligação; Catálise; Ativação Enzimática; Dados de Sequência Molecular; Ligação Proteica; Especificidade por Substrato

Palavras-chave

Catalytic promiscuity; Enzymes; Protein evolution

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Evolução Molecular / Carbono-Carbono Liases / Bacillales Idioma: En Ano de publicação: 2014 Tipo de documento: Article

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