Aiming for a shorter rheumatoid arthritis MRI protocol: can contrast-enhanced MRI replace T2 for the detection of bone marrow oedema?
Eur Radiol
; 24(10): 2614-22, 2014 Oct.
Article
em En
| MEDLINE
| ID: mdl-24972953
ABSTRACT
PURPOSE:
To determine whether T1 post-gadolinium chelate images (T1Gd) can replace T2-weighted images (T2) for evaluating bone marrow oedema (BME), thereby allowing a shorter magnetic resonance imaging (MRI) protocol in rheumatoid arthritis (RA). MATERIAL ANDMETHODS:
In 179 early arthritis patients and 43 advanced RA patients, wrist and metacarpophalangeal joints were examined on a 1.5-T extremity MRI system with a standard protocol (coronal T1, T2 fat-saturated and coronal and axial T1 fat-saturated after Gd). BME was scored according to OMERACT RAMRIS by two observers with and without T2 images available. Agreement was assessed using intraclass correlation coefficients (ICCs) for semi-quantitative scores and test characteristics with T2 images as reference.RESULTS:
Agreement between scores based on T2 and T1Gd images was excellent ICC (0.80-0.99). At bone level, sensitivity and specificity of BME on T1Gd compared to T2 were high for both patient groups and both readers (all ≥80 %).CONCLUSION:
T1Gd and T2 images are equally suitable for evaluating BME. Because contrast is usually administered to assess (teno)synovitis, a short MRI protocol of T1 and T1Gd is sufficient in RA. KEY POINTS ⢠Bone marrow oedema scores are equal on T2 and T1-Gd-chelate enhanced sequences. ⢠Agreement between scores based on T2 and T1-Gd-chelate images was excellent. ⢠Sensitivity and specificity for presence of bone marrow oedema were high. ⢠A short protocol without T2 images suffices in rheumatoid arthritis patients.
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Base de dados:
MEDLINE
Assunto principal:
Artrite Reumatoide
/
Medula Óssea
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Imageamento por Ressonância Magnética
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Meios de Contraste
/
Edema
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Articulação Metacarpofalângica
Idioma:
En
Ano de publicação:
2014
Tipo de documento:
Article