Prevalence of herpes simplex virus 1 and 2 antibodies in patients with autism spectrum disorders.
In Vivo
; 28(4): 667-71, 2014.
Article
em En
| MEDLINE
| ID: mdl-24982239
ABSTRACT
BACKGROUND/AIM:
The etiology of autism spectrum disorder (ASD) is unknown, even though it is hypothesized that a viral infection could trigger this disorder. The aim of this study was to evaluate the seropositivity rate and antibody level of Herpes Simplex Virus 1 (HSV1) and Herpes Simplex Virus 2 (HSV2) in children with ASD compared to same-aged healthy controls. PATIENTS ANDMETHODS:
We compared seropositivity rate and levels of antibodies to HSV1/2 in 54 children with ASD (19 with autistic disorder and 35 with non-autistic ASD) and in 46 controls.RESULTS:
Seropositivity rate and levels of anti-HSV1/2 were not dissimilar between cases and controls. Exposure to HSV2 was minimal.CONCLUSION:
Rate of contact with HSV1 and HSV2 assessed by the mean of detection of specific antibodies was similar between children with ASD and healthy controls.Palavras-chave
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Base de dados:
MEDLINE
Assunto principal:
Transtornos Globais do Desenvolvimento Infantil
/
Herpesvirus Humano 2
/
Herpesvirus Humano 1
/
Herpes Simples
/
Anticorpos Antivirais
Idioma:
En
Ano de publicação:
2014
Tipo de documento:
Article