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Novel human D-amino acid oxidase inhibitors stabilize an active-site lid-open conformation.
Terry-Lorenzo, Ryan T; Chun, Lawrence E; Brown, Scott P; Heffernan, Michele L R; Fang, Q Kevin; Orsini, Michael A; Pollegioni, Loredano; Hardy, Larry W; Spear, Kerry L; Large, Thomas H.
Afiliação
  • Terry-Lorenzo RT; *Discovery Research Department, Sunovion Pharmaceuticals, Marlborough, MA 01752, U.S.A.
  • Chun LE; †Emerald Bio, Bainbridge Island, WA 98110, U.S.A.
  • Brown SP; *Discovery Research Department, Sunovion Pharmaceuticals, Marlborough, MA 01752, U.S.A.
  • Heffernan ML; *Discovery Research Department, Sunovion Pharmaceuticals, Marlborough, MA 01752, U.S.A.
  • Fang QK; *Discovery Research Department, Sunovion Pharmaceuticals, Marlborough, MA 01752, U.S.A.
  • Orsini MA; *Discovery Research Department, Sunovion Pharmaceuticals, Marlborough, MA 01752, U.S.A.
  • Hardy LW; *Discovery Research Department, Sunovion Pharmaceuticals, Marlborough, MA 01752, U.S.A.
  • Spear KL; *Discovery Research Department, Sunovion Pharmaceuticals, Marlborough, MA 01752, U.S.A.
  • Large TH; *Discovery Research Department, Sunovion Pharmaceuticals, Marlborough, MA 01752, U.S.A.
Biosci Rep ; 34(4)2014 Aug 11.
Article em En | MEDLINE | ID: mdl-25001371
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Domínio Catalítico / D-Aminoácido Oxidase / Inibidores Enzimáticos Idioma: En Ano de publicação: 2014 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Domínio Catalítico / D-Aminoácido Oxidase / Inibidores Enzimáticos Idioma: En Ano de publicação: 2014 Tipo de documento: Article