Role of alanine:glyoxylate aminotransferase 2 in metabolism of asymmetric dimethylarginine in the settings of asymmetric dimethylarginine overload and bilateral nephrectomy.

Rodionov, Roman N; Martens-Lobenhoffer, Jens; Brilloff, Silke; Hohenstein, Bernd; Jarzebska, Natalia; Jabs, Normund; Kittel, Anja; Maas, Renke; Weiss, Norbert; Bode-Böger, Stefanie M

Rodionov, Roman N; Martens-Lobenhoffer, Jens; Brilloff, Silke; Hohenstein, Bernd; Jarzebska, Natalia; Jabs, Normund; Kittel, Anja; Maas, Renke; Weiss, Norbert; Bode-Böger, Stefanie M.

Afiliação

Rodionov RN; University Center for Vascular Medicine, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
Martens-Lobenhoffer J; Institute of Clinical Pharmacology, Otto-von-Guericke University, Magdeburg, Germany.
Brilloff S; University Center for Vascular Medicine, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
Hohenstein B; Division of Nephrology, Department of Internal Medicine III, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
Jarzebska N; Department of Internal Medicine III, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
Jabs N; University Center for Vascular Medicine, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
Kittel A; Institute of Experimental and Clinical Pharmacology and Toxicology, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.
Maas R; Institute of Experimental and Clinical Pharmacology and Toxicology, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.
Weiss N; University Center for Vascular Medicine, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
Bode-Böger SM; Institute of Clinical Pharmacology, Otto-von-Guericke University, Magdeburg, Germany.

Nephrol Dial Transplant ; 29(11): 2035-42, 2014 Nov.

Article em En | MEDLINE | ID: mdl-25002409

Assuntos

Injúria Renal Aguda/tratamento farmacológico; Alanina/fisiologia; Arginina/análogos & derivados; Nefrectomia; Transaminases/biossíntese; Injúria Renal Aguda/genética; Injúria Renal Aguda/metabolismo; Animais; Arginina/administração & dosagem; Arginina/farmacocinética; Biomarcadores/sangue; Biomarcadores/urina; Western Blotting; Modelos Animais de Doenças; Inibidores Enzimáticos/administração & dosagem; Inibidores Enzimáticos/farmacocinética; Regulação da Expressão Gênica; Infusões Intravenosas; Masculino; Redes e Vias Metabólicas; Camundongos; Camundongos Endogâmicos C57BL; RNA/genética; Reação em Cadeia da Polimerase em Tempo Real; Transaminases/genética

Palavras-chave

ADMA; AGXT2; DMGV; acute renal failure; nephrectomy

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Arginina / Alanina / Injúria Renal Aguda / Transaminases / Nefrectomia Idioma: En Ano de publicação: 2014 Tipo de documento: Article

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