Chondrogenic differentiation of human adipose-derived stem cells: a new path in articular cartilage defect management?
Biomed Res Int
; 2014: 740926, 2014.
Article
em En
| MEDLINE
| ID: mdl-25019085
ABSTRACT
According to data published by the Centers for Disease Control and Prevention, over 6 million people undergo a variety of medical procedures for the repair of articular cartilage defects in the U.S. each year. Trauma, tumor, and age-related degeneration can cause major defects in articular cartilage, which has a poor intrinsic capacity for healing. Therefore, there is substantial interest in the development of novel cartilage tissue engineering strategies to restore articular cartilage defects to a normal or prediseased state. Special attention has been paid to the expansion of chondrocytes, which produce and maintain the cartilaginous matrix in healthy cartilage. This review summarizes the current efforts to generate chondrocytes from adipose-derived stem cells (ASCs) and provides an outlook on promising future strategies.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Células-Tronco
/
Adipócitos
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Condrócitos
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Condrogênese
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Fraturas de Cartilagem
Idioma:
En
Ano de publicação:
2014
Tipo de documento:
Article