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Quercetin significantly inhibits the metabolism of caffeine, a substrate of cytochrome P450 1A2 unrelated to CYP1A2*1C (-2964G>A) and *1F (734C>A) gene polymorphisms.
Xiao, Jian; Huang, Wei-Hua; Peng, Jing-Bo; Tan, Zhi-Rong; Ou-Yang, Dong-Sheng; Hu, Dong-Li; Zhang, Wei; Chen, Yao.
Afiliação
  • Xiao J; Department of Clinical Pharmacology, Xiangya Hospital, Central South University, Changsha, Hunan 410008, China ; Department of Pharmacy, Xiangya Hospital, Central South University, Changsha, Hunan 410008, China.
  • Huang WH; Department of Clinical Pharmacology, Xiangya Hospital, Central South University, Changsha, Hunan 410008, China ; Hunan Key Laboratory of Pharmacogenetics, Institute of Clinical Pharmacology, Central South University, 110 Xiangya Road, Changsha, Hunan 410078, China.
  • Peng JB; Department of Clinical Pharmacology, Xiangya Hospital, Central South University, Changsha, Hunan 410008, China ; Hunan Key Laboratory of Pharmacogenetics, Institute of Clinical Pharmacology, Central South University, 110 Xiangya Road, Changsha, Hunan 410078, China.
  • Tan ZR; Department of Clinical Pharmacology, Xiangya Hospital, Central South University, Changsha, Hunan 410008, China ; Hunan Key Laboratory of Pharmacogenetics, Institute of Clinical Pharmacology, Central South University, 110 Xiangya Road, Changsha, Hunan 410078, China.
  • Ou-Yang DS; Department of Clinical Pharmacology, Xiangya Hospital, Central South University, Changsha, Hunan 410008, China ; Hunan Key Laboratory of Pharmacogenetics, Institute of Clinical Pharmacology, Central South University, 110 Xiangya Road, Changsha, Hunan 410078, China.
  • Hu DL; Department of Clinical Pharmacology, Xiangya Hospital, Central South University, Changsha, Hunan 410008, China ; Hunan Key Laboratory of Pharmacogenetics, Institute of Clinical Pharmacology, Central South University, 110 Xiangya Road, Changsha, Hunan 410078, China.
  • Zhang W; Department of Clinical Pharmacology, Xiangya Hospital, Central South University, Changsha, Hunan 410008, China ; Hunan Key Laboratory of Pharmacogenetics, Institute of Clinical Pharmacology, Central South University, 110 Xiangya Road, Changsha, Hunan 410078, China.
  • Chen Y; Department of Clinical Pharmacology, Xiangya Hospital, Central South University, Changsha, Hunan 410008, China ; Hunan Key Laboratory of Pharmacogenetics, Institute of Clinical Pharmacology, Central South University, 110 Xiangya Road, Changsha, Hunan 410078, China.
Biomed Res Int ; 2014: 405071, 2014.
Article em En | MEDLINE | ID: mdl-25025048
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Quercetina / Cafeína / Citocromo P-450 CYP1A2 Idioma: En Ano de publicação: 2014 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Quercetina / Cafeína / Citocromo P-450 CYP1A2 Idioma: En Ano de publicação: 2014 Tipo de documento: Article